Brief Information of the Cell Line and Protein
Cell Line ID: CL000112 , MDA-MB-435
 Cell Line Info 
Synonyms
MDA-MB435
MDAMB435
MDA.MB.435
MDA-435
MDA 435
MDA435
MD Anderson-Metastatic Breast-435
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0417
Protein ID: PT01786 , Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
 Protein Info 
Gene Name ENPP2
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q13822
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000112
 Cell Line Info 
 Protein ID: PT01786
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0227783
 Compound Info 
2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-1-yl)-8-ethyl-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid
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C21H20Cl2N6O3S
  2
1
IC50 = 1200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 1600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0281260
 Compound Info 
2-(4-((9H-xanthene-9-carbonyl)carbamothioyl)piperazin-1-yl)-8-ethyl-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid
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C29H26N6O5S
  2
1
IC50 = 1500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 1700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0281261
 Compound Info 
4-(2-(3-ethyl-4-oxo-3,4,6,7,8,9-hexahydropyrimido[4,5-b]quinolin-2-ylthio)acetamido)benzoic acid
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C22H22N4O4S
  1
1
IC50 = 1600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0301794
 Compound Info 
4-(4-(2-(naphthalen-1-yl)-1,3-dioxoisoindoline-5-carbonyl)phenoxy)benzoic acid
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C32H19NO6
  1
1
IC50 = 6800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0265597
 Compound Info 
4,4'-(5,5'-carbonylbis(1,3-dioxoisoindoline-5,2-diyl))bis(methylene)dibenzoic acid
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C33H20N2O9
  1
1
IC50 = 12800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0265598
 Compound Info 
3-(1,3-dioxo-2-(4-(phenyldiazenyl)phenyl)isoindoline-5-carboxamido)benzoic acid
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C28H18N4O5
  1
1
IC50 = 12800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0160898
 Compound Info 
3-(6-chloro-2-methyl-1-phenylindol-3-yl)sulfanylbenzoic acid
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C22H16ClNO2S
  1
1
IC50 < 300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0169882
 Compound Info 
6-[6-chloro-2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]sulfanylpyridine-2-carboxylic acid
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C19H15ClN4O2S
  1
1
IC50 < 300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0436386
 Compound Info 
3-[6-chloro-2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]sulfanylbenzoic acid
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C20H16ClN3O2S
  1
1
IC50 < 300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS