Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-1-yl)-8-ethyl-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid
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 PubChem ID
CID: 1302891
SID: 56418798
Canonical SMILES
CCn1cc(C(O)=O)c(=O)c2cnc(nc12)N1CCN(CC1)C(=S)Nc1cc(Cl)cc(Cl)c1
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Compound Formula C21H20Cl2N6O3S
Compound Structure
Protein Name
 Protein Info 
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
Protein Classification
Enzyme
Uniprot ID
Q13822
Gene Name
ENPP2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000111 MDA-MB-231
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 1600 nM
   TI
   LI
   LO
   TS
2
Ki = 1900 nM
   TI
   LI
   LO
   TS
CL000112 MDA-MB-435
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
2
IC50 = 1600 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1900 nM
2 Ki = 6500 nM