Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
 Cell Line Info 
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT01711 , Histamine H4 receptor
 Protein Info 
Gene Name HRH4
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q9H3N8
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053
 Cell Line Info 
 Protein ID: PT01711
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0881838
 Compound Info 
[5-(6-Fluoro-4-methyl-1H-benzoimidazol-2-yl)-4-methyl-pyrimidin-2-yl]-[3-(1-methyl-piperidin-4-yl)-propyl]-amine
   Show/Hide
C22H29FN6
  1
1
Ki = 4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0869278
 Compound Info 
TOREFORANT
   Show/Hide
C23H32N6
  1
1
Ki = 11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0902771
 Compound Info 
[5-(4,5-Difluoro-1H-benzoimidazol-2-yl)-4-methyl-pyrimidin-2-yl]-[3-(1-methyl-piperidin-4-yl)-propyl]-amine
   Show/Hide
C21H26F2N6
  1
1
Ki = 11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0967968
 Compound Info 
5-(5-Fluoro-4-methyl-1H-benzoimidazol-2-yl)-4-methyl-pyrimidin-2-yl[-3-(1-methyl-piperidin-4-yl)-propyl]-amine
   Show/Hide
C22H29FN6
  1
1
Ki = 21 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0864352
 Compound Info 
[4-Methyl-5-(4-methyl-1H-benzoimidazol-2-yl)-pyrimidin-2-yl]-[3-(1-methyl-piperidin-4-yl)-propyl]-amine
   Show/Hide
C22H30N6
  1
1
Ki = 27 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0869279
 Compound Info 
[5-(5-Fluoro-4-methyl-1H-benzoimidazol-2-yl)-4-isopropyl-pyrimidin-2-yl]-[3-(1-methyl-piperidin-4-yl)-propyl]-amine
   Show/Hide
C24H33FN6
  1
1
Ki = 230 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0863078
 Compound Info 
[5-(4,5-Dimethyl-1H-benzoimidazol-2-yl)-4-propyl-pyrimidin-2-yl]-[3-(1-methyl-piperidin-4-yl)-propyl]-amine
   Show/Hide
C25H36N6
  1
1
Ki = 2410 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS