Brief Information of the Cell Line and Protein
Cell Line ID: CL000197 , MG-63
Synonyms
M-G63
MG63
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0426
Protein ID: PT01679 , 17-beta-hydroxysteroid dehydrogenase type 2
Gene Name HSD17B2
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P37059
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000197  Protein ID: PT01679
 
Compound ID Compound Name Compound Formula
CP0352160
(4R,5R)-4-(2-fluorophenyl)-5-((S)-hydroxy(5-(pyridin-3-yl)thiophen-2-yl)methyl)-1-methylpyrrolidin-2-one
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C21H19FN2O2S
 1
1
IC50 = 30 nM
   TI
   LI
   LO
   TS
CP0308226
(4R,5R)-4-(2-fluorophenyl)-5-((S)-(5-(4-fluorophenyl)thiophen-2-yl)(hydroxy)methyl)-1-methylpyrrolidin-2-one
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C22H19F2NO2S
 1
1
IC50 = 60 nM
   TI
   LI
   LO
   TS
CP0075405
(4R,5R)-5-((S)-hydroxy(5-(pyridin-3-yl)thiophen-2-yl)methyl)-1-methyl-4-phenylpyrrolidin-2-one
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C21H20N2O2S
 1
1
IC50 = 90 nM
   TI
   LI
   LO
   TS
CP0531972
(4R,5R)-5-((S)-(5-(4-fluorophenyl)thiophen-2-yl)(hydroxy)methyl)-1-methyl-4-phenylpyrrolidin-2-one
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C22H20FNO2S
 1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS
CP0221602
(4R,5R)-5-((S)-hydroxy(5-(phenylsulfonyl)thiophen-2-yl)methyl)-1-methyl-4-phenylpyrrolidin-2-one
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C22H21NO4S2
 1
1
IC50 = 480 nM
   TI
   LI
   LO
   TS