Brief Information of the Cell Line and Protein
Cell Line ID: CL000007 , HT-29
Synonyms
HT 29
HT29
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0320
Protein ID: PT01650 , Alpha-2A adrenergic receptor
Gene Name ADRA2A
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P08913
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000007  Protein ID: PT01650
 
Compound ID Compound Name Compound Formula
CP0372472
1-((R)-2-aminopropyl)-1H-indazol-6-ol
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C10H13N3O
 1
1
EC50 = 1990 nM
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CP0044585
1-((S)-2-aminopropyl)-1H-indazol-6-ol
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C10H13N3O
 1
1
EC50 = 2600 nM
   TI
   LI
   LO
   TS
CP0795457
SID50107142
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C21H27ClN2O3
 1
1
Ki = 1.8 nM
   TI
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CP0037622
2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole
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C11H12N2O2
 1
1
Ki = 8 nM
   TI
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CP0434061
4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-7-methoxy-N-(quinuclidin-3-yl)benzofuran-2-carboxamide
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C29H35N3O5
 1
1
Ki = 42 nM
   TI
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CP0495766
6,7-dimethoxy-2-((7-methoxy-2-(pyridin-2-yl)benzofuran-4-yl)methyl)-1,2,3,4-tetrahydroisoquinoline
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C26H26N2O4
 1
1
Ki = 135 nM
   TI
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CP0371793
N-(2-amino-2-methylpropyl)-4-[(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)methyl]-7-methoxy-1-benzofuran-2-carboxamide
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C26H33N3O5
 1
1
Ki = 141 nM
   TI
   LI
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CP0371791
(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-7-methoxybenzofuran-2-yl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone
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C31H39N3O5
 1
1
Ki = 186 nM
   TI
   LI
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   TS
CP0504965
2-((2-(furan-2-yl)-7-methoxybenzofuran-4-yl)methyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
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C25H25NO5
 1
1
Ki = 204 nM
   TI
   LI
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CP0371790
3-(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-7-methoxybenzofuran-2-yl)-N-(2-(dimethylamino)ethyl)benzamide
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C32H37N3O5
 1
1
Ki = 216 nM
   TI
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CP0533128
6,7-dimethoxy-2-((7-methoxy-2-(2-(trifluoromethyl)phenyl)benzofuran-4-yl)methyl)-1,2,3,4-tetrahydroisoquinoline
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C28H26F3NO4
 1
1
Ki = 304 nM
   TI
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CP0515166
8-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-f]pyrimidin-5-amine
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C21H22N6O3
 1
1
Ki = 400 nM
   TI
   LI
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   TS
CP0371748
4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-N-(2-(dimethylamino)ethyl)-7-methoxybenzofuran-2-carboxamide
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C26H33N3O5
 1
1
Ki = 454 nM
   TI
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   TS
CP0371788
2-((2-(2-fluorophenyl)-7-methoxybenzofuran-4-yl)methyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
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C27H26FNO4
 1
1
Ki = 857 nM
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CP0372244
6,7-dimethoxy-2-((7-methoxy-2-phenylbenzofuran-4-yl)methyl)-1,2,3,4-tetrahydroisoquinoline
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C27H27NO4
 1
1
Ki = 1742 nM
   TI
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CP0371789
6,7-dimethoxy-2-((7-methoxy-2-(3-methoxyphenyl)benzofuran-4-yl)methyl)-1,2,3,4-tetrahydroisoquinoline
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C28H29NO5
 1
1
Ki = 2552 nM
   TI
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CP0854701
1-[(2-Bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole Dimesylate Monohydrate
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C22H30BrN3O7S2
 1
1
Ki = 2570 nM
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