Brief Information of the Cell Line and Protein
Cell Line ID: CL000043 , U2OS
 Cell Line Info 
Synonyms
U-2 OS
U-2OS
U-2-OS
U2-OS
U20-S
U20S
2T
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0042
Protein ID: PT01591 , Thyroid hormone receptor alpha
 Protein Info 
Gene Name THRA
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P10827
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000043
 Cell Line Info 
 Protein ID: PT01591
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0026502
 Compound Info 
(2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid
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C15H12I3NO4
  1
1
EC50 = 2.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0646460
 Compound Info 
5-(4-(4-hydroxy-3-isopropylphenoxy)-3,5-diiodobenzyl)imidazolidine-2,4-dione
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C19H18I2N2O4
  1
1
EC50 = 34 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0823542
 Compound Info 
5-(4-(3-ethyl-4-hydroxyphenoxy)-3,5-diiodobenzyl)imidazolidine-2,4-dione
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C18H16I2N2O4
  1
1
EC50 = 87 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0748742
 Compound Info 
5-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodobenzyl)imidazolidine-2,4-dione
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C16H11I3N2O4
  1
1
EC50 = 105 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0843267
 Compound Info 
5-(3,5-dibromo-4-(4-hydroxy-3-isopropylphenoxy)benzyl)imidazolidine-2,4-dione
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C19H18Br2N2O4
  1
1
EC50 = 128 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0733970
 Compound Info 
5-(4-(3-cyclopropyl-4-hydroxyphenoxy)-3,5-diiodobenzyl)imidazolidine-2,4-dione
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C19H16I2N2O4
  1
1
EC50 = 145 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0647090
 Compound Info 
5-(4-(4-hydroxy-3-methylphenoxy)-3,5-diiodobenzyl)imidazolidine-2,4-dione
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C17H14I2N2O4
  1
1
EC50 = 146 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0647089
 Compound Info 
5-(4-(4-hydroxy-3-bromophenoxy)-3,5-diiodobenzyl)imidazolidine-2,4-dione
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C16H11BrI2N2O4
  1
1
EC50 = 206 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0700404
 Compound Info 
5-(4-(4-hydroxy-3-methoxyphenoxy)-3,5-diiodobenzyl)imidazolidine-2,4-dione
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C17H14I2N2O5
  1
1
EC50 = 870 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0893813
 Compound Info 
5-(4-(4-hydroxyphenoxy)-3,5-diiodobenzyl)imidazolidine-2,4-dione
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C16H12I2N2O4
  1
1
EC50 > 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS