Brief Information of the Cell Line and Protein
Cell Line ID: CL000035 , NIH 3T3
Synonyms
NIH/3T3
NIH-3T3
NIH3T3
3T3
3T3NIH
3T3-Swiss
Swiss-3T3
Swiss/3T3
Swiss 3T3
Swiss3T3
Category Spontaneously immortalized cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0594
Protein ID: PT01577 , Androgen receptor
Gene Name AR
Organism Mus musculus, Mouse
Protein Classification Transcription factor
Uniprot ID P19091
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000035  Protein ID: PT01577
 
Compound ID Compound Name Compound Formula
CP0860903
2-Chloro-4-(3-endo-hydroxy-3-exo-methyl-8-aza-bicyclo[3.2.1]oct-8-yl)-3-methylbenzonitrile
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C16H19ClN2O
 1
1
EC50 = 1 nM
   TI
   LI
   LO
   TS
CP0036705
(1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one
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C19H28O2
 1
1
EC50 = 1.995 nM
   TI
   LI
   LO
   TS
CP0859392
4-(3-endo-Hydroxy-3-exo-cyclopropyl 8-azabicyclo[3.2.1]oct-8-yl)naphthalene-1-carbonitrile
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C21H22N2O
 1
1
EC50 = 1.995 nM
   TI
   LI
   LO
   TS
CP0874917
4-(3-endo-Hydroxy-3-exo-methyl 8-azabicyclo[3.2.1]oct-8-yl)naphthalene-1-carbonitrile
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C19H20N2O
 1
1
EC50 = 1.995 nM
   TI
   LI
   LO
   TS
CP0914105
2-Chloro-4-(3-endo-hydroxy-8-azabicyclo[3.2.1]octan-8-yl)-3-methylbenzonitrile
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C15H17ClN2O
 1
1
EC50 = 1.995 nM
   TI
   LI
   LO
   TS
CP0918258
4-(3-endo-Hydroxy-3-exo-vinyl 8-azabicyclo[3.2.1]oct-8-yl)naphthalene-1-carbonitrile
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C20H20N2O
 1
1
EC50 = 1.995 nM
   TI
   LI
   LO
   TS
CP0044960
(1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-5-one
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C19H30O2
 1
1
EC50 = 3.981 nM
   TI
   LI
   LO
   TS
CP0431033
4-[(1S,5S)-8-azabicyclo[3.2.1]octan-8-yl]naphthalene-1-carbonitrile
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C18H18N2
 1
1
EC50 = 3.981 nM
   TI
   LI
   LO
   TS
CP0919071
4-(3-endo-Hydroxy-3-exo-ethyl 8-azabicyclo[3.2.1]oct-8-yl)naphthalene-1-carbonitrile
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C20H22N2O
 1
1
EC50 = 3.981 nM
   TI
   LI
   LO
   TS
CP0919070
4-(3-endo-Hydroxy-3-exo-isopropyl 8-azabicyclo[3.2.1]oct-8-yl)naphthalene-1-carbonitrile
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C21H24N2O
 1
1
EC50 = 5.012 nM
   TI
   LI
   LO
   TS
CP0058400
1-(4-nitronaphthalen-1-yl)pyrrolidine
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C14H14N2O2
 1
1
EC50 = 6.31 nM
   TI
   LI
   LO
   TS
CP0879770
endo-8-(2,3-Dimethyl-4-nitro-phenyl)-8-azabicyclo[3.2.1]octan-3-ol
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C15H20N2O3
 1
1
EC50 = 12.59 nM
   TI
   LI
   LO
   TS
CP0148231
4-pyrrolidin-1-ylnaphthalene-1-carbonitrile
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C15H14N2
 1
1
EC50 = 15.85 nM
   TI
   LI
   LO
   TS
CP0879772
4-(3-endo-Hydroxy-3-exo-n-propyl-8-azabicyclo[3.2.1.]oct-8-yl)naphthalene-1-carbonitrile
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C21H24N2O
 1
1
EC50 = 15.85 nM
   TI
   LI
   LO
   TS
CP0916359
4-(endo-3-Methoxy-8-azabicyclo[3.2.1]oct-8-yl)naphthalene-1-carbonitrile
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C19H20N2O
 1
1
EC50 = 19.95 nM
   TI
   LI
   LO
   TS
CP0401449
4-[(1R,5R)-3-oxo-8-azabicyclo[3.2.1]octan-8-yl]naphthalene-1-carbonitrile
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C18H16N2O
 1
1
EC50 = 100 nM
   TI
   LI
   LO
   TS