General Information of the Compound
Compound ID
CP0879770
Compound Name
endo-8-(2,3-Dimethyl-4-nitro-phenyl)-8-azabicyclo[3.2.1]octan-3-ol
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Formula
C15H20N2O3
Molecular Weight
276.336
Canonical SMILES
Cc1c(N2[C@@H]3CC[C@H]2C[C@@H](O)C3)ccc([N+](=O)[O-])c1C
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InChI
InChI=1S/C15H20N2O3/c1-9-10(2)15(17(19)20)6-5-14(9)16-11-3-4-12(16)8-13(18)7-11/h5-6,11-13,18H,3-4,7-8H2,1-2H3/t11-,12+,13+
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InChIKey
XBMKKDIGFFDSDN-ITGUQSILSA-N
Physicochemical Property
logP
2.70374
Rotatable Bonds
2
Heavy Atom Count
20
Polar Areas
66.61
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
20

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL3084688
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01577, Androgen receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
EC50 = 12.59 nM
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