| Compound ID |
Compound Name |
Compound Formula |
|
CP0225027
|
N-[(2R)-1-morpholin-4-ylpropan-2-yl]-6-(8-pyridin-4-ylimidazo[4,5-c][1,7]naphthyridin-1-yl)quinolin-2-amine
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|
C30H28N8O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0203515
|
N-(1-morpholin-4-ylpropan-2-yl)-6-(8-pyridin-4-ylimidazo[4,5-c][1,7]naphthyridin-1-yl)quinolin-2-amine
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|
C30H28N8O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0300593
|
N-(1-morpholin-4-ylpropan-2-yl)-6-(8-phenylimidazo[4,5-c][1,7]naphthyridin-1-yl)-1,3-benzothiazol-2-amine
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|
C29H27N7OS
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0300594
|
N-(1-morpholin-4-ylpropan-2-yl)-6-(8-pyridin-4-ylimidazo[4,5-c][1,7]naphthyridin-1-yl)-1,3-benzothiazol-2-amine
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|
C28H26N8OS
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0300592
|
N-(2-morpholin-4-ylethyl)-6-(8-phenylimidazo[4,5-c][1,7]naphthyridin-1-yl)-1,3-benzothiazol-2-amine
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|
C28H25N7OS
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0229225
|
1-quinolin-6-yl-8-thiophen-3-ylimidazo[4,5-c][1,7]naphthyridine
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|
C22H13N5S
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0179259
|
N-(1-morpholin-4-ylpropan-2-yl)-6-(8-thiophen-2-ylimidazo[4,5-c][1,7]naphthyridin-1-yl)-1,3-benzothiazol-2-amine
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|
C27H25N7OS2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0321384
|
N-[(2S)-1-morpholin-4-ylpropan-2-yl]-6-(8-pyridin-4-ylimidazo[4,5-c][1,7]naphthyridin-1-yl)quinolin-2-amine
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|
C30H28N8O
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0516522
|
1-(3H-benzimidazol-5-yl)-8-thiophen-3-ylimidazo[4,5-c][1,7]naphthyridine
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|
C20H12N6S
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0461465
|
2-[4-(8-thiophen-3-ylimidazo[4,5-c][1,7]naphthyridin-1-yl)phenyl]acetonitrile
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|
C21H13N5S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0445878
|
2-methyl-6-(8-phenylimidazo[4,5-c][1,7]naphthyridin-1-yl)-1,3-benzothiazole
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|
C23H15N5S
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0518032
|
1-(3H-benzimidazol-5-yl)-8-phenylimidazo[4,5-c][1,7]naphthyridine
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|
C22H14N6
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0507068
|
8-phenyl-1-quinolin-6-ylimidazo[4,5-c][1,7]naphthyridine
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|
C24H15N5
|
1
|
| 1 |
IC50 = 96 nM
|
|
|
|
CP0573881
|
1-(3H-benzimidazol-5-yl)-8-pyridin-4-ylimidazo[4,5-c][1,7]naphthyridine
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|
C21H13N7
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0445876
|
1-(3H-benzimidazol-5-yl)-8-(1H-pyrazol-4-yl)imidazo[4,5-c][1,7]naphthyridine
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|
C19H12N8
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0507067
|
4-[1-(3H-benzimidazol-5-yl)imidazo[4,5-c][1,7]naphthyridin-8-yl]-1,2-thiazole
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|
C19H11N7S
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0431367
|
1-(3H-benzimidazol-5-yl)-8-(3-methylphenyl)imidazo[4,5-c][1,7]naphthyridine
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|
C23H16N6
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0573880
|
1-(3H-benzimidazol-5-yl)-8-pyridin-3-ylimidazo[4,5-c][1,7]naphthyridine
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|
C21H13N7
|
1
|
| 1 |
IC50 = 670 nM
|
|
|
|
CP0511816
|
2-[4-(7-chloro-8-thiophen-3-ylimidazo[4,5-c]quinolin-1-yl)phenyl]acetonitrile
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|
C22H13ClN4S
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0473246
|
1-(3H-benzimidazol-5-yl)-8-(cyclohexen-1-yl)imidazo[4,5-c][1,7]naphthyridine
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|
C22H18N6
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0525621
|
1-(3H-benzimidazol-5-yl)-8-(4-methylphenyl)imidazo[4,5-c][1,7]naphthyridine
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|
C23H16N6
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0516521
|
2-[4-(8-thiophen-3-ylimidazo[4,5-c]quinolin-1-yl)phenyl]acetonitrile
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|
C22H14N4S
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0445877
|
1-(3H-benzimidazol-5-yl)-8-piperidin-1-ylimidazo[4,5-c][1,7]naphthyridine
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|
C21H19N7
|
1
|
| 1 |
IC50 = 3500 nM
|
|
|
|
CP0431368
|
1-(3H-benzimidazol-5-yl)-8-chloroimidazo[4,5-c][1,7]naphthyridine
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|
C16H9ClN6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0026322
|
N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzamide
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|
C16H14F3IN2O4
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
