Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(1-morpholin-4-ylpropan-2-yl)-6-(8-thiophen-2-ylimidazo[4,5-c][1,7]naphthyridin-1-yl)-1,3-benzothiazol-2-amine
    Show/Hide
 PubChem ID
CID: 134140223
Canonical SMILES
CC(CN1CCOCC1)Nc1nc2ccc(cc2s1)-n1cnc2cnc3cnc(cc3c12)-c1cccs1
    Show/Hide
Compound Formula C27H25N7OS2
Compound Structure
Protein Name
 Protein Info 
Mitogen-activated protein kinase kinase kinase 8
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE11 family
Uniprot ID
P41279
Gene Name
MAP3K8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 22 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 280 nM
2 IC50 = 290 nM