| Compound ID |
Compound Name |
Compound Formula |
|
CP0385267
|
6-[[(1R,2S)-2-aminocyclohexyl]amino]-4-(3-methylanilino)-3-oxo-1,2-dihydropyrrolo[3,4-c]pyridine-7-carbonitrile
Show/Hide
|
C21H24N6O
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0447379
|
6-[[(1R,2S)-2-aminocyclohexyl]amino]-7-chloro-4-(3-methylanilino)-1,2-dihydropyrrolo[3,4-c]pyridin-3-one
Show/Hide
|
C20H24ClN5O
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0876093
|
6-((1R,2S)-2-aminocyclohexylamino)-7-(1H-pyrazol-4-yl)-4-(m-tolylamino)-1H-pyrrolo[3,4-c]pyridin-3(2H)-one
Show/Hide
|
C23H27N7O
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0240497
|
6-[[(1R,2S)-2-aminocyclohexyl]amino]-7-fluoro-4-(3-methylanilino)-1,2-dihydropyrrolo[3,4-c]pyridin-3-one
Show/Hide
|
C20H24FN5O
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0237328
|
6-[[(1R,2S)-2-aminocyclohexyl]amino]-3-oxo-4-pyrazolo[1,5-a]pyridin-3-yl-1,2-dihydropyrrolo[3,4-c]pyridine-7-carbonitrile
Show/Hide
|
C21H21N7O
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0004106
|
(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one
Show/Hide
|
C28H26N4O3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0386247
|
6-[[(1R,2S)-2-aminocyclohexyl]amino]-7-methyl-4-(3-methylanilino)-1,2-dihydropyrrolo[3,4-c]pyridin-3-one
Show/Hide
|
C21H27N5O
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0190764
|
6-[[(1R,2S)-2-aminocyclohexyl]amino]-7-fluoro-4-(1-methylpyrazol-4-yl)-1,2-dihydropyrrolo[3,4-c]pyridin-3-one
Show/Hide
|
C17H21FN6O
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
|
CP0105423
|
5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethoxyphenylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
|
C20H26N8O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0117949
|
2-[2-(1H-thieno[3,2-c]pyrazol-3-yl)-1H-indol-6-yl]propan-2-ol
Show/Hide
|
C16H15N3OS
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0432915
|
6-[[(1R,2S)-2-aminocyclohexyl]amino]-4-(3-methylanilino)-1,2-dihydropyrrolo[3,4-c]pyridin-3-one
Show/Hide
|
C20H25N5O
|
1
|
| 1 |
IC50 = 4.7 nM
|
|
|
|
CP0440526
|
5-[[(1S,2R)-2-aminocyclohexyl]amino]-7-(3,5-dimethoxyanilino)imidazo[1,2-c]pyrimidine-8-carboxamide
Show/Hide
|
C21H27N7O3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0441431
|
5-[[(1S,2R)-2-aminocyclohexyl]amino]-7-(3,5-dimethylanilino)imidazo[1,2-c]pyrimidine-8-carboxamide
Show/Hide
|
C21H27N7O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0400103
|
3-[5-(5-ethoxy-6-fluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-1,1-diethylurea
Show/Hide
|
C17H21FN6O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0163895
|
5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethoxyphenylamino)-[1,2,4]triazolo[4,3-c]pyrimidine-8-carboxamide
Show/Hide
|
C20H26N8O3
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0067678
|
2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-(3-methylanilino)-6,7-dihydropyrrolo[3,4-d]pyrimidin-5-one
Show/Hide
|
C19H24N6O
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0440524
|
5-((1S,2R)-2-Aminocyclohexylamino)-7-(3,5-dimethoxyphenylamino)-2-phenylimidazo[1,2-c]pyrimidine-8-carboxamide
Show/Hide
|
C27H31N7O3
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0419013
|
5-[[(1S,2R)-2-aminocyclohexyl]amino]-7-(3,5-difluoroanilino)imidazo[1,2-c]pyrimidine-8-carboxamide
Show/Hide
|
C19H21F2N7O
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0468542
|
5-[[(1S,2R)-2-aminocyclohexyl]amino]-7-(3-methoxyanilino)imidazo[1,2-c]pyrimidine-8-carboxamide
Show/Hide
|
C20H25N7O2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0424378
|
5-[[(1S,2R)-2-aminocyclohexyl]amino]-7-(4-methoxyanilino)imidazo[1,2-c]pyrimidine-8-carboxamide
Show/Hide
|
C20H25N7O2
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0155921
|
3-[2-(1H-thieno[3,2-c]pyrazol-3-yl)-1H-indol-6-yl]pentan-3-ol
Show/Hide
|
C18H19N3OS
|
1
|
| 1 |
IC50 = 185.6 nM
|
|
|
|
CP0440525
|
5-[(2-aminoethyl)amino]-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidine-8-carboxamide
Show/Hide
|
C17H21N7O3
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0092874
|
3-[4-(2-morpholin-4-ylethoxy)-2-(1H-thieno[3,2-c]pyrazol-3-yl)-1H-indol-6-yl]pentan-3-ol
Show/Hide
|
C24H30N4O3S
|
1
|
| 1 |
IC50 = 286.9 nM
|
|
|
|
CP0126833
|
3-[2-[5-(difluoromethyl)-1H-thieno[3,2-c]pyrazol-3-yl]-1H-indol-6-yl]pentan-3-ol
Show/Hide
|
C19H19F2N3OS
|
1
|
| 1 |
IC50 = 358.2 nM
|
|
|
|
CP0313084
|
5-((1R,2S)-2-Aminocyclohexylamino)-7-(3,5-dimethoxyphenylamino)-2-phenylimidazo[1,2-c]pyrimidine-8-carboxamide
Show/Hide
|
C27H31N7O3
|
1
|
| 1 |
IC50 = 380 nM
|
|
|
|
CP0440528
|
7-(3,5-dimethoxyanilino)-5-[[(1S,2R)-2-hydroxycyclohexyl]amino]imidazo[1,2-c]pyrimidine-8-carboxamide
Show/Hide
|
C21H26N6O4
|
1
|
| 1 |
IC50 = 720 nM
|
|
|
|
CP0444648
|
5-(2-Amino-2-methylpropylamino)-7-(3,5-dimethoxyphenylamino)-2-phenylimidazo[1,2-c]pyrimidine-8-carboxamide
Show/Hide
|
C25H29N7O3
|
1
|
| 1 |
IC50 = 840 nM
|
|
|
|
CP0246601
|
3-[3-(4-methoxyphenyl)-2-(1H-thieno[3,2-c]pyrazol-3-yl)-1H-indol-6-yl]pentan-3-ol
Show/Hide
|
C25H25N3O2S
|
1
|
| 1 |
IC50 = 938.6 nM
|
|
|
|
CP0138955
|
7-(3,5-Dimethoxyphenylamino)-5-(2-methylcyclohexylamino)imidazo[1,2-c]pyrimidine-8-carboxamide
Show/Hide
|
C22H28N6O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0441432
|
5-[[(1S,2S)-2-aminocyclohexyl]amino]-7-(3,5-dimethoxyanilino)imidazo[1,2-c]pyrimidine-8-carboxamide
Show/Hide
|
C21H27N7O3
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0441429
|
5-(3-Aminopropylamino)-7-(3,5-dimethoxyphenylamino)imidazo[1,2-c]pyrimidine-8-carboxamide
Show/Hide
|
C18H23N7O3
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0150694
|
3-[2-(5-phenyl-1H-thieno[3,2-c]pyrazol-3-yl)-1H-indol-6-yl]pentan-3-ol
Show/Hide
|
C24H23N3OS
|
1
|
| 1 |
IC50 = 2469 nM
|
|
|
|
CP0377798
|
7-[(3,5-dimethoxyphenyl)amino]-5-[(2-hydroxyethyl)amino]imidazo[1,2-a]pyrimidine-8-carboxamide
Show/Hide
|
C17H20N6O4
|
1
|
| 1 |
IC50 = 4300 nM
|
|
|
|
CP0453795
|
5-amino-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidine-8-carboxamide
Show/Hide
|
C15H16N6O3
|
1
|
| 1 |
IC50 = 7100 nM
|
|
|
|
CP0495996
|
5-[[(1S,2R)-2-aminocyclohexyl]amino]-7-(2-methoxyanilino)imidazo[1,2-c]pyrimidine-8-carboxamide
Show/Hide
|
C20H25N7O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
