| Compound ID |
Compound Name |
Compound Formula |
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CP0944208
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5-(4-(3-((6-(tert-Butylsulfonyl)-4-((4,5-dimethyl-1H-pyrazol-3-yl)-amino)quinazolin-7-yl)oxy)propyl)piperazin-1-yl)-N-((3S,5S)-1-((S)-3,3-dimethyl-2-((S)-2-(methylamino)propanamido)butanoyl)-5-(((R)-1,2,3,4-tetrahydronaphthalen-1-yl)carbamoyl)pyrrolidin-3-yl)pyrazine-2-carboxamide
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C53H70N14O7S
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1
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| 1 |
IC50 = 0.1 nM
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CP0966877
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(S)-N-((S)-1-(1-(5-(4-(2-((6-(tert-Butylsulfonyl)-4-(((4,5-dimethyl-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)ethyl)piperazin-1-yl)-pyrazine-2-carbonyl)piperidin-4-yl)-2-(S)-2-(4-(4-fluorobenzoyl)-thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)-propanamide
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C53H67FN14O7S2
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1
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| 1 |
IC50 = 0.1585 nM
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CP0559658
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(2S,4S)-4-[[2-[2-[2-[2-[2-[4-(1,3-benzothiazol-5-ylamino)-6-tert-butylsulfonylquinolin-7-yl]oxyethoxy]ethoxy]ethoxy]ethoxy]acetyl]amino]-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[(1R)-1-phenylpropyl]pyrrolidine-2-carboxamide
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C54H74N8O11S2
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1
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| 1 |
IC50 = 1.995 nM
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CP0550778
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(2S)-N-[(1S)-1-[1-[2-[2-[2-[2-[2-[4-(1,3-benzothiazol-5-ylamino)-6-tert-butylsulfonylquinolin-7-yl]oxyethoxy]ethoxy]ethoxy]ethoxy]acetyl]piperidin-4-yl]-2-[(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl]-2-(methylamino)propanamide
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C55H67FN8O11S3
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1
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| 1 |
IC50 = 5.012 nM
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CP0968793
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(5S,8S,10aR)-3-(5-(4-(3-((6-(tert-butylsulfonyl)-4-((4,5-dimethyl-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)propyl)piperazin-1-yl)pyrazine-2-carbonyl)-5-((S)-2-(methylamino)propanamido)-6-oxo-N-(1,2,3,4-tetrahydronaphthalen-1-yl)decahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide
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C53H70N14O7S
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1
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| 1 |
IC50 = 6.31 nM
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CP0944190
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(S)-N-((S)-1-(1-(2-(4-(3-((6-(tert-Butylsulfonyl)-4-((4,5-dimethyl-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)propyl)piperazin-1-yl)-pyrimidine-5-carbonyl)piperidin-4-yl)-2-((S)-2-(4-(4-fluorobenzoyl)-thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)-propanamide
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C54H67FN14O7S2
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1
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| 1 |
IC50 = 7.943 nM
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CP0962680
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2-((2R,5R)-2-(((R)-4-(5-(4-(3-((6-(tert-Butylsulfonyl)-4-((3,4-dimethyl-1H-pyrazol-5-yl)amino)quinazolin-7-yl)oxy)propyl)-piperazine-1-carbonyl)pyrimidin-2-yl)-2-methylpiperazin-1-yl)-methyl)-5-methylpiperazin-1-yl)-1-(6-(4-fluorobenzyl)-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-b]pyridin-1-yl)ethanone
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C59H78FN15O6S
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1
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| 1 |
IC50 = 7.943 nM
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CP0533814
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(3R)-7-[2-[2-[2-[2-[4-(1,3-benzothiazol-5-ylamino)-6-tert-butylsulfonylquinolin-7-yl]oxyethoxy]ethoxy]ethoxy]ethoxy]-2-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
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C58H73N7O10S2
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1
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| 1 |
IC50 = 10 nM
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CP0868240
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(S)-N-((S)-1-(1-(6-(4-(3-((6-(tert-Butylsulfonyl)-4-((4,5-dimethyl-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)propyl)piperazin-1-yl)-nicotinoyl)piperidin-4-yl)-2-((S)-2-(4-(4-fluorobenzoyl)thiazol-2-yl)-pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)propanamide
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C55H68FN13O7S2
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1
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| 1 |
IC50 = 10 nM
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CP0953690
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(5S,8S,10aR)-3-(5-(4-(3-((6-(tert-Butylsulfonyl)-4-((4,5-dimethyl-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)propyl)piperazin-1-yl)-pyrazine-2-carbonyl)-5-((S)-2-(methylamino)propanamido)-6-oxo-N-((R)-1,2,3,4-Tetrahydronaphthalen-1-yl)decahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide
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C50H66F2N14O7S
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1
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| 1 |
IC50 = 10 nM
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CP0963888
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(S)-N-((S)-1-(1-(2-(4-(((6-(tert-Butylsulfonyl)-4-((4,5-dimethyl-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)methyl)piperidin-1-yl)-pyrimidine-5-carbonyl)piperidin-4-yl)-2-((S)-2-(4-(4-fluorobenzoyl)-thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)-propanamide
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C53H64FN13O7S2
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1
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| 1 |
IC50 = 10 nM
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CP0965435
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(S)-N-((S)-1-(1-(5-(4-(3-(6-(tert-butylsulfonyl)-4-(4,5-dimethyl-1H-pyrazol-3-ylamino)quinazolin-7-yloxy)propyl)piperazin-1-yl)pyrazine-2-carbonyl)piperidin-4-yl)-2-((S)-2-(4-(4-fluorobenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)propanamide
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C54H67FN14O7S2
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1
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| 1 |
IC50 = 12.59 nM
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CP0966674
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5-(4-(3-((6-(tert-butylsulfonyl)-4-((4,5-dimethyl-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)propyl)piperazin-1-yl)-N-((3S)-1-((S)-3,3-dimethyl-2-((S)-2-(methylamino)propanamido)butanoyl)-5-((1,2,3,4-tetrahydronaphthalen-1-yl)carbamoyl)pyrrolidin-3-yl)pyrazine-2-carboxamide
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C54H74N14O7S
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1
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| 1 |
IC50 = 12.59 nM
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CP0963889
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5-(4-(3-(6-(tert-butylsulfonyl)-4-(4,5-dimethyl-1H-pyrazol-3-ylamino)quinazolin-7-yloxy)propyl)piperazin-1-yl)-N-((3S,5S)-5-(2,6-difluorophenylcarbamoyl)-1-((S)-3,3-dimethyl-2-((R)-2-(methylamino)propanamido)butanoyl)pyrrolidin-3-yl)pyrazine-2-carboxamide
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C58H76FN15O5S
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1
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| 1 |
IC50 = 25.12 nM
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CP0965481
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(S)-N-((S)-1-(1-(4-(4-(3-((6-(tert-Butylsulfonyl)-4-((4,5-dimethyl-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)propyl)piperazin-1-yl)-benzoyl)piperidin-4-yl)-2-((S)-2-(4-(4-fluorobenzoyl)thiazol-2-yl)-pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)propanamide
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C56H69FN12O7S2
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1
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| 1 |
IC50 = 31.62 nM
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CP0966876
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(S)-N-((S)-1-(1-(2-(4-(3-((6-(tert-Butylsulfonyl)-4-((4,5-dimethyl-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)propyl)piperidin-1-yl)-pyrimidine-5-carbonyl)Piperidin-4-yl)-2-((S)-2-(4-(4-fluorobenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)propanamide
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C55H68FN13O7S2
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1
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| 1 |
IC50 = 31.62 nM
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CP0969474
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(S)-N-((S)-1-(1-(2-(4-(2-((6-(tert-Butylsulfonyl)-4-((4,5-dimethyl-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)ethyl)piperidin-1-yl)-pyrimidine-5-carbonyl)piperidin-4-yl)-2-((S)-2-(4-(4-fluorobenzoyl)-thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)-propanamide
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C54H66FN13O7S2
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1
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| 1 |
IC50 = 39.81 nM
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CP0960425
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(S)-N-((S)-1-(1-(6-(4-(2-((6-(tert-Butylsulfonyl)-4-((4,5-dimethyl-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)ethyl)piperazin-1-yl)-nicotinoyl)piperidin-4-yl)-2-((S)-2-(4-(4-fluorobenzoyl)thiazol-2-yl)-pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)propanamide
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C54H66FN13O7S2
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1
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| 1 |
IC50 = 125.89 nM
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CP0953689
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(S)-N-((S)-1-(1-(14-((6-(tert-Butylsulfonyl)-4-((4,5-dimethyl-1H-pyrazol-3-yl)amino)quinazolin-7-l)oxy)-3,6,9,12-tetraoxatetradecanoyl)piperidin-4-yl)-2-((S)-2-(4-(4-fluorobenzoyl)-thiazol-2-l)pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)-propanamide
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C52H69FN10O11S2
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1
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| 1 |
IC50 = 158.49 nM
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CP0962679
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(S)-N-((S)-1-(1-(5-(4-(2-(6-(tert-butylsulfonyl)-4-(4,5-dimethyl-1H-pyrazol-3-ylamino)quinazolin-7-yloxy)ethyl)piperazin-1-yl)pyrazine-2-carbonyl)piperidin-4-yl)-2-((S)-2-(4-(4-fluorobenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)propanamide
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C53H65FN14O7S2
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1
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| 1 |
IC50 = 158.49 nM
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CP0969151
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(S)-N-((S)-1-(1-(2-(4-(2-((6-(tert-Butylsulfonyl)-4-((4,5-dimethyl-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)ethyl)piperazin-1-yl)-pyrimidine-5-carbonyl)piperidin-4-yl)-2-((S)-2-(4-(4-fluorobenzoyl)-thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)-propanamide
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C53H65FN14O7S2
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1
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| 1 |
IC50 = 251.19 nM
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CP0953688
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(S)-7-(2-(2-(2-(2-((6-(tert-Butylsulfonyl)-4-((4,5-dimethyl-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)ethoxy)ethoxy)ethoxy)-ethoxy)-2-((S)-3,3-dimethyl-2-((S)-2-(methylamino)propanamido)-butanoyl)-N-((R)-1,2,3,4-tetrahydronaphthalen-1-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
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C55H75N9O10S
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1
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| 1 |
IC50 = 398.11 nM
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