Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-((2R,5R)-2-(((R)-4-(5-(4-(3-((6-(tert-Butylsulfonyl)-4-((3,4-dimethyl-1H-pyrazol-5-yl)amino)quinazolin-7-yl)oxy)propyl)-piperazine-1-carbonyl)pyrimidin-2-yl)-2-methylpiperazin-1-yl)-methyl)-5-methylpiperazin-1-yl)-1-(6-(4-fluorobenzyl)-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-b]pyridin-1-yl)ethanone
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 PubChem ID
CID: 132045972
Canonical SMILES
Cc1[nH]nc(Nc2ncnc3cc(OCCCN4CCN(C(=O)c5cnc(N6CCN(C[C@H]7CN[C@H](C)CN7CC(=O)N7CC(C)(C)c8c7cc(Cc7ccc(F)cc7)c(=O)n8C)[C@H](C)C6)nc5)CC4)c(S(=O)(=O)C(C)(C)C)cc23)c1C
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Compound Formula C59H78FN15O6S
Compound Structure
Protein Name
 Protein Info 
Receptor-interacting serine/threonine-protein kinase 2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase RIPK family
Uniprot ID
O43353
Gene Name
RIPK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000699 HCC4006
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 7.943 nM
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