5-(3-{(S)-1-[4-(1-Hydroxy-heptyl)-phenyl]-5-oxo-pyrrolidin-2-yl}-propyl)-thiophene-2-carboxylic acid

5-(3-{(S)-1-[4-(1-Hydroxy-hexyl)-phenyl]-5-oxo-pyrrolidin-2-yl}-propyl)-thiophene-2-carboxylic acid

7-((1R,2S,3R,5R)-3,5-dichloro-2-(4-(1-hydroxyhexyl)phenyl)cyclopentyl)hept-5-enoic acid

5-{(R)-1-[4-(1-Hydroxy-heptyl)-phenyl]-5-oxo-pyrrolidin-2-ylmethoxymethyl}-thiophene-2-carboxylic acid

5-(3-((1R,2S)-2-(4-(1-hydroxyhexyl)phenyl)-5-oxocyclopentyl)propyl)thiophene-2-carboxylic acid

7-[(1R,2S)-2-[4-(1-hydroxyhexyl)phenyl]-5-oxocyclopentyl]heptanoic acid

5-{(R)-1-[4-(1-Hydroxy-hexyl)-phenyl]-5-oxo-pyrrolidin-2-ylmethoxymethyl}-thiophene-2-carboxylic acid

7-((1R,2S,3S,5R)-3,5-dichloro-2-(4-(1-hydroxyhexyl)phenyl)cyclopentyl)hept-5-enoic acid

7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)cyclopentyl)hept-5-enoic acid

7-((1R,2S)-2-(4-(1-hydroxyhexyl)phenyl)-5-oxocyclopentyl)hept-5-enoic acid

5-(3-((2R)-1-(4-(1-hydroxyhexyl)phenyl)-5-oxopyrrolidin-2-yl)allyl)thiophene-2-carboxylic acid

7-((1R,2S,3R)-3-hydroxy-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)-5-oxocyclopentyl)hept-5-enoic acid

5-{(R)-1-[4-(1-Hydroxy-hexyl)-phenyl]-5-oxo-pyrrolidin-2-ylmethoxymethyl}-furan-2-carboxylic acid

7-((1R,2S,3R,5R)-2-(4-tert-butylphenyl)-5-chloro-3-hydroxycyclopentyl)hept-5-enoic acid

5-{3-[(S)-1-(4-Hexanoyl-phenyl)-5-oxo-pyrrolidin-2-yl]-propyl}-thiophene-2-carboxylic acid

7-[2-(3-hydroxyoctyl)-6-oxopyridin-1-yl]heptanoic acid

7-((1R,2S)-2-(3-((R)-hydroxy(1-propylcyclobutyl)methyl)phenyl)-5-oxocyclopentyl)hept-5-enoic acid

methyl 7-((1R,2S)-2-(4-(1-hydroxyhexyl)phenyl)-5-oxocyclopentyl)heptanoate

7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)cyclopentyl)heptanoic acid

7-((1R,2S,3R)-2-(4-tert-butylphenyl)-3-hydroxy-5-oxocyclopentyl)heptanoic acid

7-((1R,2S)-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)-5-oxocyclopentyl)heptanoic acid

methyl 7-((1R,2S,3R,5R)-2-(4-tert-butylphenyl)-5-chloro-3-hydroxycyclopentyl)hept-5-enoate

methyl 7-((1R,2S,3R)-3-hydroxy-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)-5-oxocyclopentyl)heptanoate

methyl 7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)cyclopentyl)hept-5-enoate

methyl 7-((1R,2S,3R)-2-(4-tert-butylphenyl)-3-hydroxy-5-oxocyclopentyl)heptanoate

7-((1R,2S,3R,5R)-2-(4-tert-butylphenyl)-5-chloro-3-hydroxycyclopentyl)heptanoic acid

methyl 7-((1R,2S,3R)-2-(2,3-dihydro-1H-inden-5-yl)-3-hydroxy-5-oxocyclopentyl)heptanoate

5-[(R)-1-(4-tert-Butyl-phenyl)-5-oxo-pyrrolidin-2-ylmethoxymethyl]-furan-2-carboxylic acid

methyl 7-((1R,2S,3R)-3-hydroxy-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)-5-oxocyclopentyl)hept-5-enoate

7-((1S,2S,3R,5R)-5-cyano-3-hydroxy-2-(4-(1-hydroxyhexyl)phenyl)cyclopentyl)hept-5-enoic acid

4-[2-[3,5-dichloro-2-[(E)-3-hydroxyoct-1-enyl]-6-oxopyridin-1-yl]ethyl]benzoic acid

4-[2-[3,5-dichloro-2-(3-hydroxyoctyl)-6-oxopyridin-1-yl]ethyl]benzoic acid

4-[2-[3,5-dichloro-2-[(E)-3-hydroxy-3-methyloct-1-enyl]-6-oxopyridin-1-yl]ethyl]benzoic acid

7-[3,5-dibromo-2-[(E)-3-hydroxyoct-1-enyl]-6-oxopyridin-1-yl]heptanoic acid

7-[3,5-dichloro-2-[(E)-3-hydroxyoct-1-enyl]-6-oxopyridin-1-yl]heptanoic acid

methyl 7-((1R,2S)-2-(4-(1-hydroxyhexyl)phenyl)-5-oxocyclopentyl)hept-5-enoate

5-[(R)-1-(4-tert-Butyl-phenyl)-5-oxo-pyrrolidin-2-ylmethoxymethyl]-thiophene-2-carboxylic acid

7-[(S)-1-(4-tert-Butyl-phenyl)-5-oxo-pyrrolidin-2-yl]-heptanoic acid

US11149018, Example 34

5-{3-[(S)-2-(4-biphenyl-3-yl-3-hydroxy-butyl)-5-oxo-pyrrolidin-1-yl]-propyl}-thiophene-2-carboxylic acid

2-[2-[4-(4-ethylphenyl)benzoyl]-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid

2-[8-chloro-2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid

2-[2-(3-chlorobenzoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid

2-[2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid

2-[6-chloro-2-(3-chlorobenzoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid

2-[2-(3-chlorobenzoyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid

2-[8-fluoro-2-[2-(1H-indol-3-yl)acetyl]-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid

2-[8-fluoro-2-(thiophene-2-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid

2-[2-benzoyl-8-(trifluoromethyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid

2-(2-benzoyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)acetic acid

2-[8-fluoro-2-(3-naphthalen-1-ylpropanoyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid

2-[6-chloro-2-[4-(4-ethylphenyl)benzoyl]-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid

2-[8-fluoro-2-(2-naphthalen-1-ylacetyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid

ACT-129968

2-[8-methyl-2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid

2-[2-(cyclohexanecarbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid

2-[6-chloro-8-fluoro-2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid

2-(2-benzoyl-8-propan-2-yl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)acetic acid

2-(2-benzoyl-8-methoxy-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)acetic acid

2-[2-(naphthalene-1-carbonyl)-8-(trifluoromethyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid

7-((S)-2-((R)-3-hydroxy-4-(3-(methoxymethyl)phenyl)butyl)-5-oxopyrrolidin-1-yl)heptanoic acid

5-(3-((S)-2-(4-(4-chlorophenyl)-3-hydroxybutyl)-5-oxopyrrolidin-1-yl)propyl)thiophene-2-carboxylic acid

4-(3-(2-(3-hydroxy-4-phenylbutyl)-5-oxopyrrolidin-1-yl)propyl)benzoic acid

4-(3-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxopyrrolidin-1-yl)propyl)benzoic acid

7-((S)-2-(3-hydroxy-4-phenylbutyl)-5-oxopyrrolidin-1-yl)heptanoic acid

4-(3-(2-(4-(4-fluorophenyl)-3-hydroxybutyl)-5-oxopyrrolidin-1-yl)propyl)benzoic acid

7-((S)-2-(3-hydroxy-4-(3-phenoxyphenyl)butyl)-5-oxopyrrolidin-1-yl)heptanoic acid

(15S)-prostaglandin E2

2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl}-cyclopropanecarboxylic acid

(E)-3-{2-[(E)-3-(2-Benzyloxy-3-methyl-phenyl)-allyl]-phenyl}-acrylic acid

3-[2-[3-(2-phenylmethoxyphenyl)phenyl]phenyl]-N-thiophen-2-ylsulfonylpropanamide

3-[2''-(2,6-Dichloro-benzyloxy)-[1,1';3',1'']terphenyl-2-yl]-propionic acid

3-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl}-propionic acid

(E)-3-[2-(3,4-dichlorophenyl)phenyl]-N-thiophen-2-ylsulfonylprop-2-enamide

3-{2-[4-(2-Benzyloxy-phenyl)-thiophen-2-yl]-phenyl}-propionic acid

3-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl}-butyric acid

2-[2-[5-(2-phenylmethoxyphenyl)thiophen-3-yl]anilino]acetic acid

3-(2-Benzyloxy-[1,1';3',1'']terphenyl-2''-yl)-propionic acid

(E)-3-(2-Benzyloxy-[1,1';3',1'']terphenyl-2''-yl)-acrylic acid

3-(2-Phenoxymethyl-[1,1';3',1'']terphenyl-2''-yl)-propionic acid

APD-811

CHEMBL3933704

US9180116, 2C

US9180116, 9C

2-[(3R)-5-bromo-4-[(4-chlorophenyl)methyl]-7-fluoro-2,3-dihydro-1H-cyclopenta[b]indol-3-yl]acetic acid

3-{2-[5-(2-Benzyloxy-phenyl)-thiophen-2-yl]-phenyl}-propionic acid

4-(2-Benzyloxy-[1,1';3',1'']terphenyl-2''-yl)-butyric acid

3-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl}-2-methyl-propionic acid

3-[1,1';3',1'']Terphenyl-2-yl-propionic acid

3-(2''-Benzyloxy-[1,1';3',1'']terphenyl-2-yl)-2-methyl-propionic acid

7-[(2R)-2-[(E,3S,4S)-3-hydroxy-4-methylnon-1-en-6-ynyl]-5-oxopyrrolidin-1-yl]heptanoic acid

2-[(3R)-4-[(4-chlorophenyl)methyl]-7-fluoro-5-methylsulfonyl-2,3-dihydro-1H-cyclopenta[b]indol-3-yl]acetic acid

7-[(R)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-pyrrolidin-1-yl]-heptanoic acid

2-[(3R)-5-acetyl-4-[(4-chlorophenyl)methyl]-7-fluoro-2,3-dihydro-1H-cyclopenta[b]indol-3-yl]acetic acid

7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxy-2-methylpropyl)phenyl)cyclopentyl)hept-5-enoic acid

3-(4''-Benzyloxy-[1,1';3',1'']terphenyl-2-yl)-propionic acid

(E)-3-(3',4'-Dichloro-biphenyl-2-yl)-acrylic acid

(2''-Benzyloxy-[1,1';3',1'']terphenyl-2-yl)-acetic acid

4-[3-(2-Benzyloxy-phenyl)-propyl]-benzoic acid

1-(2,6-dimethoxyphenyl)-N-[[3-methyl-4-[6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-8H-pyrrolo[3,4-g]quinolin-7-yl]phenyl]methylsulfonyl]cyclopropane-1-carboxamide

7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxy-2-methylpropyl)phenyl)cyclopentyl)heptanoic acid

5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-octahydropentalen-2-ylidene]pentanoic acid

N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]-2-(2-methoxyphenyl)acetamide

4-(2-((R)-2-((S)-3-hydroxyhept-1-enyl)-5-oxopyrrolidin-1-yl)ethyl)benzoate

4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrrolidin-1-yl)ethyl)benzoic acid

4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrrolidin-1-yl)ethyl)benzoic acid

2-((R)-4-(4-chlorobenzyl)-5-(1-hydroxyethyl)-7-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid

(R)-2-(4-(4-chlorobenzyl)-5-acetyl-7-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid