Brief Information of the Cell Line and Protein
Cell Line ID: CL000025 , HEK-293T
 Cell Line Info 
Synonyms
Hek293T
HEK-293T
HEK 293T
HEK-293-T
HEK 293 T
293-T
293 T
293T
Human Embryonic Kidney 293T
293tsA1609neo
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0063
Protein ID: PT01307 , 5-hydroxytryptamine receptor 4
 Protein Info 
Gene Name HTR4
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q13639
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000025
 Cell Line Info 
 Protein ID: PT01307
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0071840
 Compound Info 
5-[(1-propylpiperidin-4-yl)methoxy]benzo[h][1,6]naphthyridine
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C21H25N3O
  2
1
EC50 = 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 7.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0071842
 Compound Info 
4-fluoro-6-[(1-propylpiperidin-4-yl)methoxy]phenanthridine
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C22H25FN2O
  2
1
EC50 = 63.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 3.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0057051
 Compound Info 
4-methoxy-6-[(1-propylpiperidin-4-yl)methoxy]phenanthridine
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C23H28N2O2
  2
1
EC50 = 79.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 17 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0057054
 Compound Info 
4-chloro-6-[(1-propylpiperidin-4-yl)methoxy]phenanthridine
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C22H25ClN2O
  2
1
EC50 = 251 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0501064
 Compound Info 
3-fluoro-6-[(1-propylpiperidin-4-yl)methoxy]phenanthridine
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C22H25FN2O
  1
1
Ki = 33 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0381166
 Compound Info 
5-[(1-propylpiperidin-4-yl)methoxy]benzo[c][2,6]naphthyridine
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C21H25N3O
  1
1
Ki = 403 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0244206
 Compound Info 
7-[4-imidazo[1,2-a]pyridin-5-yl-3-(trifluoromethyl)phenoxy]thieno[2,3-c]pyridine
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C21H12F3N3OS
  1
1
Ki = 3700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0064183
 Compound Info 
4-[3-methyl-4-(6-methylimidazo[1,2-a]pyrazin-5-yl)phenoxy]furo[3,2-c]pyridine
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C21H16N4O2
  1
1
Ki = 9100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0064188
 Compound Info 
4-[4-(6-methylimidazo[1,2-a]pyrazin-5-yl)-3-(trifluoromethyl)phenoxy]furo[3,2-c]pyridine
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C21H13F3N4O2
  1
1
Ki > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0369306
 Compound Info 
4-[4-imidazo[1,2-a]pyridin-5-yl-3-(trifluoromethyl)phenoxy]furo[3,2-c]pyridine
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C21H12F3N3O2
  1
1
Ki > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS