| Compound ID |
Compound Name |
Compound Formula |
|
CP0072521
|
3-[[[2-(hydroxyamino)-2-oxoethyl]-(4-methoxyphenyl)sulfonylamino]methyl]benzoic acid
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C17H18N2O7S
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
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CP0448794
|
2-[[4-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]phenyl]sulfonylamino]acetic acid
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|
C22H21N3O5S2
|
2
|
| 1 |
IC50 = 1.6 nM
|
|
|
| 2 |
Ki = 1.8 nM
|
|
|
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CP0159065
|
N-[(2S)-1-[[(1R,2R)-2-hydroxycyclohexyl]amino]-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
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|
C30H36N4O5S
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
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CP0117836
|
5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(1S)-2-(methylamino)-1-(oxan-4-yl)-2-oxoethyl]furan-2-carboxamide
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|
C27H29FN4O5S
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
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CP0407818
|
(2S)-3-methyl-2-[[4-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]phenyl]sulfonylamino]butanoic acid
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|
C25H27N3O5S2
|
2
|
| 1 |
IC50 = 2.2 nM
|
|
|
| 2 |
Ki = 2.3 nM
|
|
|
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CP0117839
|
N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
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|
C26H29FN4O4S
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
|
CP0235665
|
5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-3-hydroxy-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
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|
C25H27FN4O5S
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0353851
|
5-[3-fluoro-4-[(6-fluoro-4-oxo-3H-quinazolin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
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|
C26H24F2N4O4S
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0099232
|
5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C25H27FN4O4S
|
2
|
| 1 |
IC50 = 2.7 nM
|
|
|
| 2 |
Ki = 1.7 nM
|
|
|
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CP0081310
|
N-(2-aminoethyl)-4-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]benzenesulfonamide
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|
C22H24N4O3S2
|
2
|
| 1 |
IC50 = 3.4 nM
|
|
|
| 2 |
Ki = 13.5 nM
|
|
|
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CP0117834
|
5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2R)-3-methyl-1-(oxetan-3-ylamino)-1-oxobutan-2-yl]furan-2-carboxamide
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|
C27H29FN4O5S
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0228998
|
N-[(1S)-1-cyclohexyl-2-(methylamino)-2-oxoethyl]-5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C28H31FN4O4S
|
2
|
| 1 |
IC50 = 4.4 nM
|
|
|
| 2 |
IC50 = 6.3 nM
|
|
|
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CP0253210
|
5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-1-[[(1R,2R)-2-hydroxycyclohexyl]amino]-3-methyl-1-oxobutan-2-yl]furan-2-carboxamide
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|
C30H35FN4O5S
|
1
|
| 1 |
IC50 = 5.1 nM
|
|
|
|
CP0235666
|
N-[(2S)-1-[[(2S)-2,3-dihydroxypropyl]amino]-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
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|
C27H32N4O6S
|
1
|
| 1 |
IC50 = 5.5 nM
|
|
|
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CP0081669
|
N-[(2R)-1-[[(2S)-2,3-dihydroxypropyl]amino]-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
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|
C27H32N4O6S
|
1
|
| 1 |
IC50 = 6.4 nM
|
|
|
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CP0159067
|
5-[3-fluoro-4-[[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)amino]methyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C25H28FN5O4
|
1
|
| 1 |
IC50 = 6.4 nM
|
|
|
|
CP0412434
|
N-[(2R)-1-[[(2R)-2,3-dihydroxypropyl]amino]-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C27H32N4O6S
|
1
|
| 1 |
IC50 = 6.9 nM
|
|
|
|
CP0487778
|
(2R)-3-methyl-2-[[4-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]phenyl]sulfonylamino]butanoic acid
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|
C25H27N3O5S2
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
Ki = 1.6 nM
|
|
|
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CP0068681
|
2-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C24H26FN5O3S2
|
2
|
| 1 |
IC50 = 7.1 nM
|
|
|
| 2 |
IC50 = 14.9 nM
|
|
|
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CP0159080
|
N-[(2S)-1-[[(2R)-2,3-dihydroxypropyl]amino]-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C27H32N4O6S
|
1
|
| 1 |
IC50 = 7.1 nM
|
|
|
|
CP0117832
|
N-[(2S)-1-(3-hydroxypropylamino)-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C27H32N4O5S
|
1
|
| 1 |
IC50 = 7.3 nM
|
|
|
|
CP0117838
|
N-[(2R)-1-(3-hydroxypropylamino)-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C27H32N4O5S
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0159084
|
5-[3-fluoro-4-[(4-oxo-3H-thieno[2,3-d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C24H23FN4O4S2
|
1
|
| 1 |
IC50 = 8.4 nM
|
|
|
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CP0236957
|
N-[(1S)-1-cyclopropyl-2-(methylamino)-2-oxoethyl]-5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C25H25FN4O4S
|
1
|
| 1 |
IC50 = 8.5 nM
|
|
|
|
CP0159064
|
N-[(2S)-1-(cyclopropylamino)-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C27H30N4O4S
|
1
|
| 1 |
IC50 = 9.1 nM
|
|
|
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CP0099230
|
N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C25H28N4O4S
|
1
|
| 1 |
IC50 = 9.4 nM
|
|
|
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CP0370129
|
5-[3-fluoro-4-[(4-oxo-3H-quinazolin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C26H25FN4O4S
|
1
|
| 1 |
IC50 = 9.4 nM
|
|
|
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CP0228996
|
N-(2-hydroxyethyl)-4-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]benzenesulfonamide
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|
C22H23N3O4S2
|
2
|
| 1 |
IC50 = 12 nM
|
|
|
| 2 |
Ki = 9.2 nM
|
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|
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CP0068679
|
N-[(2S)-1-(2-aminoethylamino)-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C26H31N5O4S
|
1
|
| 1 |
IC50 = 12.9 nM
|
|
|
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CP0353852
|
5-[3-fluoro-4-[(5-methyl-4-oxo-3H-thieno[2,3-d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C25H25FN4O4S2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
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CP0387333
|
N-[(2R)-1-(2-aminoethylamino)-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C26H31N5O4S
|
1
|
| 1 |
IC50 = 14.4 nM
|
|
|
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CP0081308
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N-[(1R,2R)-2-aminocyclohexyl]-4-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]benzenesulfonamide
Show/Hide
|
C26H30N4O3S2
|
1
|
| 1 |
IC50 = 16.9 nM
|
|
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CP0205581
|
N-[(1R,2S)-2-aminocyclohexyl]-4-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]benzenesulfonamide
Show/Hide
|
C26H30N4O3S2
|
1
|
| 1 |
IC50 = 17.9 nM
|
|
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CP0353850
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N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]-2-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-1,3-oxazole-4-carboxamide
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|
C24H27N5O4S
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
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CP0117840
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5-[3-fluoro-4-[2-(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)ethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C26H29FN4O4
|
1
|
| 1 |
IC50 = 18.7 nM
|
|
|
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CP0069584
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N-[(2R)-1-(azetidin-3-ylamino)-3-methyl-1-oxobutan-2-yl]-5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C27H30FN5O4S
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
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CP0159066
|
N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]-5-[6-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]pyridin-3-yl]furan-2-carboxamide
Show/Hide
|
C24H27N5O4S
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
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CP0159082
|
5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[1-(methylcarbamoyl)cyclohexyl]furan-2-carboxamide
Show/Hide
|
C27H29FN4O4S
|
1
|
| 1 |
IC50 = 43.2 nM
|
|
|
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CP0068695
|
5-[3-fluoro-4-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C23H25FN4O4S
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
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CP0387332
|
N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]-2-[6-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]pyridin-3-yl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C23H26N6O3S2
|
1
|
| 1 |
IC50 = 148 nM
|
|
|
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CP0159068
|
5-[3-fluoro-4-[(6-oxo-1H-pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C22H23FN4O4S
|
1
|
| 1 |
IC50 = 153 nM
|
|
|
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CP0159081
|
N-[(1R)-1-cyclohexyl-2-(methylamino)-2-oxoethyl]-5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C28H31FN4O4S
|
1
|
| 1 |
IC50 = 159 nM
|
|
|
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CP0117835
|
5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2R)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C25H27FN4O4S
|
1
|
| 1 |
IC50 = 257 nM
|
|
|
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CP0117842
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5-[3-fluoro-4-[(4-oxo-1,5-dihydropyrazolo[3,4-d]pyrimidin-6-yl)sulfanylmethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C23H23FN6O4S
|
1
|
| 1 |
IC50 = 274 nM
|
|
|
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CP0220110
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N-[(2R)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C26H29FN4O4S
|
1
|
| 1 |
IC50 = 289 nM
|
|
|
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CP0109466
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N-[(2R)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C25H28N4O4S
|
1
|
| 1 |
IC50 = 356 nM
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CP0159083
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5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)oxymethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C25H27FN4O5
|
1
|
| 1 |
IC50 = 697 nM
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CP0220111
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5-[3-fluoro-4-[[6-oxo-4-(trifluoromethyl)-1H-pyrimidin-2-yl]sulfanylmethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C23H22F4N4O4S
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1
|
| 1 |
IC50 = 1200 nM
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|
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CP0068693
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5-[3-fluoro-4-[(5-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C23H25FN4O4S
|
1
|
| 1 |
IC50 = 1300 nM
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|
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CP0068689
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5-[3-fluoro-4-[(4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
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C24H24FN5O4S
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1
|
| 1 |
IC50 = 2000 nM
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|
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CP0065111
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2-[(4-methylphenyl)methylsulfanyl]-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-one
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C15H16N2OS
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2
|
| 1 |
IC50 = 2400 nM
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|
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| 2 |
Ki = 800 nM
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CP0068691
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5-[3-fluoro-4-[(5-fluoro-6-oxo-1H-pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C22H22F2N4O4S
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1
|
| 1 |
IC50 = 2600 nM
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|
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CP0069583
|
5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2R)-1-[[(1R,2R)-2-hydroxycyclohexyl]amino]-3-methyl-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C30H35FN4O5S
|
1
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| 1 |
IC50 > 5000 nM
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|
|
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CP0117833
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N-[(2R)-1-[[(1R,2R)-2-hydroxycyclohexyl]amino]-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C30H36N4O5S
|
1
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| 1 |
IC50 > 5000 nM
|
|
|
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CP0117841
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5-[3-fluoro-4-[[(4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-2-yl)amino]methyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C24H25FN6O4
|
1
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| 1 |
IC50 > 5000 nM
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|
|
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CP0236976
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2-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-3-methyl-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]imidazole-4-carboxamide
Show/Hide
|
C25H29FN6O3S
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1
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| 1 |
IC50 > 5000 nM
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|
|
