Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01250 , A disintegrin and metalloproteinase with thrombospondin motifs 5
 Protein Info 
Gene Name ADAMTS5
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q9UNA0
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT01250
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0038344
 Compound Info 
(2S,3R)-2-(cyclopropylmethylamino)-N1-hydroxy-N4-((1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)-3-(3-hydroxybenzyl)succinamide
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C24H29N3O5
  1
1
IC50 = 17 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0234042
 Compound Info 
2-[[4-[(2-chloro-4-fluorophenyl)methoxy]phenyl]sulfonylamino]-N-hydroxyacetamide
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C15H14ClFN2O5S
  1
1
IC50 = 35 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0144469
 Compound Info 
N-hydroxy-2-[(4-phenoxyphenyl)sulfonylamino]acetamide
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C14H14N2O5S
  1
1
IC50 = 330 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0035896
 Compound Info 
GM6001
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C20H28N4O4
  1
1
IC50 = 500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0109082
 Compound Info 
N-hydroxy-2-[(4-phenylmethoxyphenyl)sulfonylamino]acetamide
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C15H16N2O5S
  1
1
IC50 = 620 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0218336
 Compound Info 
N-hydroxy-3-[(4-phenoxyphenyl)sulfonylamino]propanamide
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C15H16N2O5S
  1
1
IC50 = 1410 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0127842
 Compound Info 
N-hydroxy-2-[2-methylpropyl-(4-phenylmethoxyphenyl)sulfonylamino]acetamide
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C19H24N2O5S
  1
1
IC50 = 1770 nM
 Bioactivity Info 
   TI
   LI
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CP0136690
 Compound Info 
2-(4-Butoxy-benzenesulfonylamino)-N-hydroxy-acetamide
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C12H18N2O5S
  1
1
IC50 = 3400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0115111
 Compound Info 
N-hydroxy-2-[(6-phenoxypyridin-3-yl)sulfonylamino]acetamide
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C13H13N3O5S
  1
1
IC50 = 3500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS