| Compound ID |
Compound Name |
Compound Formula |
|
CP0106900
|
2-[4-[4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypiperidin-1-yl]-N-methylacetamide
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|
C23H25ClFN5O3
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0877209
|
4-(3-Chloro-2,4-difluoroanilino)-7-methoxy-6-{[1-(N-methylcarbamoylmethyl)piperidin-4-yl]oxy}quinazoline
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|
C23H24ClF2N5O3
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0058458
|
2-(4-(4-(3-chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)piperidin-1-yl)acetamide
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|
C22H23ClFN5O3
|
1
|
| 1 |
IC50 = 107 nM
|
|
|
|
CP0935441
|
4-(3-Chloro-2-fluoroanilino)-6-{[1-(N-ethylcarbamoylmethyl)piperidin-4-yl]oxy}-7-methoxyquinazoline
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|
C24H27ClFN5O3
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0935439
|
rac-4-(3-Chloro-2-fluoroanilino)-7-methoxy-6-{[1-(N-methylcarbamoylmethyl)piperidin-3-yl]oxy}quinazoline
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|
C23H25ClFN5O3
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0874352
|
4-(3-Chloro-2-fluoroanilino)-7-methoxy-6-{[1-(N-(2-methoxyethyl)carbamoylmethyl)piperidin-4-yl]oxy}quinazoline
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|
C25H29ClFN5O4
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0960075
|
rac-4-(3-Chloro-2-fluoroanilino)-7-methoxy-6-{[1-(N-methylcarbamoylmethyl)pyrrolidin-3-yl]oxy}quinazoline
Show/Hide
|
C22H23ClFN5O3
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0874350
|
4-(3-Chloro-4-fluoroanilino)-7-methoxy-6-{[1-(N-methylcarbamoylmethyl)piperidin-4-yl]oxy}quinazoline
Show/Hide
|
C23H25ClFN5O3
|
1
|
| 1 |
IC50 = 264 nM
|
|
|
|
CP0935440
|
4-(3-Chloroanilino)-7-methoxy-6-{[1-(N-methylcarbamoylmethyl)piperidin-4-yl]oxy}quinazoline
Show/Hide
|
C23H26ClN5O3
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0861264
|
4-(3-Chloro-2-fluoroanilino)-6-{[1-(N-isopropylcarbamoylmethyl)piperidin-4-yl]oxy}-7-methoxyquinazoline
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|
C25H29ClFN5O3
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0936769
|
4-(3-Chloro-2-fluoroanilino)-7-methoxy-6-{[1-(N-methylcarbamoylethyl)piperidin-4-yl]oxy}quinazoline
Show/Hide
|
C24H27ClFN5O3
|
1
|
| 1 |
IC50 = 550 nM
|
|
|
|
CP0959497
|
4-(3-Chloro-2-fluoroanilino)-6-{[1-(N,N-dimethylcarbamoylmethyl)piperidin-4-yl]oxy}-7-methoxyquinazoline
Show/Hide
|
C24H27ClFN5O3
|
1
|
| 1 |
IC50 = 670 nM
|
|
|
|
CP0966762
|
4-(5-Chloro-2-fluoroanilino)-7-methoxy-6-{[1-(N-methylcarbamoylmethyl)piperidin-4-yl]oxy}quinazoline
Show/Hide
|
C23H25ClFN5O3
|
1
|
| 1 |
IC50 = 860 nM
|
|
|
|
CP0874349
|
4-(3-Chloro-2-fluoroanilino)-7-methoxy-6-{[1-(N-methylcarbamoylmethyl)azetidin-3-yl]oxy}quinazoline
Show/Hide
|
C21H21ClFN5O3
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0874348
|
4-(3-Chloro-2-fluoroanilino)-7-methoxy-6-{2-[N-(N'-methylcarbamoylmethyl)-N-methylamino]ethoxy}quinazoline
Show/Hide
|
C21H23ClFN5O3
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
