Brief Information of the Compound and Protein
Compound Name
4-(3-Chloro-2-fluoroanilino)-6-{[1-(N-isopropylcarbamoylmethyl)piperidin-4-yl]oxy}-7-methoxyquinazoline
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PubChem ID
CID: 72165162
Canonical SMILES
COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OC1CCN(CC(=O)NC(C)C)CC1
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Compound Formula C25H29ClFN5O3
Compound Structure
Protein Name
Receptor tyrosine-protein kinase erbB-2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P04626
Gene Name
ERBB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000919 MCF-7 cl.24 Homo sapiens (Human)  1
1
IC50 = 410 nM
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