Brief Information of the Compound and Protein
Compound Name
4-(3-Chloro-2-fluoroanilino)-7-methoxy-6-{[1-(N-methylcarbamoylmethyl)azetidin-3-yl]oxy}quinazoline
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PubChem ID
CID: 72163263
Canonical SMILES
CNC(=O)CN1CC(Oc2cc3c(Nc4cccc(Cl)c4F)ncnc3cc2OC)C1
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Compound Formula C21H21ClFN5O3
Compound Structure
Protein Name
Receptor tyrosine-protein kinase erbB-2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P04626
Gene Name
ERBB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000919 MCF-7 cl.24 Homo sapiens (Human)  1
1
IC50 = 1100 nM
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