| Compound ID |
Compound Name |
Compound Formula |
|
CP0474324
|
N-[2-(2-fluoro-5-methylphenyl)-5-methylpyridin-4-yl]-1-methylpyrazolo[4,3-b]pyridin-7-amine
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|
C20H18FN5
|
1
|
| 1 |
EC50 = 6.31 nM
|
|
|
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CP0315152
|
N-[2-(2,5-difluorophenyl)-5-methylpyridin-4-yl]-1H-pyrazolo[4,3-b]pyridin-7-amine
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|
C18H13F2N5
|
1
|
| 1 |
EC50 = 7.943 nM
|
|
|
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CP0393841
|
1-[7-[[2-(2,5-difluorophenyl)-5-methylpyridin-4-yl]amino]pyrazolo[4,3-b]pyridin-1-yl]propan-2-ol
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|
C21H19F2N5O
|
1
|
| 1 |
EC50 = 7.943 nM
|
|
|
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CP0412916
|
1-ethyl-N-[2-(2-fluoro-5-methylphenyl)-5-methylpyridin-4-yl]pyrazolo[4,3-b]pyridin-7-amine
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|
C21H20FN5
|
1
|
| 1 |
EC50 = 7.943 nM
|
|
|
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CP0315153
|
2-[7-[[2-(5-chloro-2-fluorophenyl)-5-methylpyridin-4-yl]amino]pyrazolo[4,3-b]pyridin-2-yl]acetamide
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|
C20H16ClFN6O
|
1
|
| 1 |
EC50 = 12.59 nM
|
|
|
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CP0540708
|
2-ethyl-N-[2-(2-fluoro-5-methylphenyl)-5-methylpyridin-4-yl]pyrazolo[4,3-b]pyridin-7-amine
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|
C21H20FN5
|
1
|
| 1 |
EC50 = 15.85 nM
|
|
|
|
CP0334618
|
2-[7-[[2-(5-chloro-2-fluorophenyl)-5-methylpyridin-4-yl]amino]pyrazolo[4,3-b]pyridin-1-yl]acetamide
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|
C20H16ClFN6O
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
|
CP0493466
|
7-[[2-(2,5-difluorophenyl)pyridin-4-yl]amino]-N-methylpyrazolo[4,3-b]pyridine-1-carboxamide
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|
C19H14F2N6O
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
|
CP0523179
|
2-[7-[[2-(2-fluoro-5-methylphenyl)-5-methylpyridin-4-yl]amino]pyrazolo[4,3-b]pyridin-1-yl]ethanol
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|
C21H20FN5O
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
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CP0493468
|
7-[[2-(2,5-difluorophenyl)-5-methylpyridin-4-yl]amino]-N-methylpyrazolo[4,3-b]pyridine-1-carboxamide
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|
C20H16F2N6O
|
1
|
| 1 |
EC50 = 25.12 nM
|
|
|
|
CP0547980
|
7-[[2-(5-chloro-2-fluorophenyl)pyridin-4-yl]amino]-N-methylpyrazolo[4,3-b]pyridine-1-carboxamide
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|
C19H14ClFN6O
|
1
|
| 1 |
EC50 = 25.12 nM
|
|
|
|
CP0081501
|
N-[2-(5-chloro-2-fluorophenyl)-5-methylpyridin-4-yl]-1H-pyrazolo[4,3-b]pyridin-7-amine
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|
C18H13ClFN5
|
1
|
| 1 |
EC50 = 31.62 nM
|
|
|
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CP0412932
|
7-[[2-(2,5-difluorophenyl)pyridin-4-yl]amino]-N-ethylpyrazolo[4,3-b]pyridine-1-carboxamide
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|
C20H16F2N6O
|
1
|
| 1 |
EC50 = 31.62 nM
|
|
|
|
CP0520362
|
5-methoxy-N-[5-methyl-2-(6-methylpyridin-2-yl)pyridin-4-yl]quinolin-4-amine
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|
C22H20N4O
|
1
|
| 1 |
EC50 = 31.62 nM
|
|
|
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CP0562903
|
7-[[2-(5-chloro-2-fluorophenyl)-5-methylpyridin-4-yl]amino]-N-methylpyrazolo[4,3-b]pyridine-1-carboxamide
Show/Hide
|
C20H16ClFN6O
|
1
|
| 1 |
EC50 = 31.62 nM
|
|
|
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CP0412914
|
N-[2-(2,5-difluorophenyl)pyridin-4-yl]-1H-pyrazolo[4,3-b]pyridin-7-amine
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|
C17H11F2N5
|
1
|
| 1 |
EC50 = 39.81 nM
|
|
|
|
CP0521197
|
N-[2-(5-chloro-2-fluorophenyl)pyridin-4-yl]-1H-pyrazolo[4,3-b]pyridin-7-amine
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|
C17H11ClFN5
|
1
|
| 1 |
EC50 = 50.12 nM
|
|
|
|
CP0393790
|
(2S)-1-[7-[[2-(2-fluoro-5-methylphenyl)-5-methylpyridin-4-yl]amino]pyrazolo[4,3-b]pyridin-1-yl]propan-2-ol
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|
C22H22FN5O
|
1
|
| 1 |
EC50 = 63.1 nM
|
|
|
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CP0474293
|
(2S)-1-[7-[[2-(2-fluoro-5-methylphenyl)-5-methylpyridin-4-yl]amino]pyrazolo[4,3-b]pyridin-2-yl]propan-2-ol
Show/Hide
|
C22H22FN5O
|
1
|
| 1 |
EC50 = 79.43 nM
|
|
|
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CP0487809
|
N-[2-(2-fluoro-5-methylphenyl)-5-methylpyridin-4-yl]-2-methylpyrazolo[4,3-b]pyridin-7-amine
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|
C20H18FN5
|
1
|
| 1 |
EC50 = 79.43 nM
|
|
|
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CP0234761
|
2-[7-[[2-(5-chloro-2-fluorophenyl)pyridin-4-yl]amino]pyrazolo[4,3-b]pyridin-2-yl]acetamide
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|
C19H14ClFN6O
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0474325
|
(2R)-1-[7-[[2-(2-fluoro-5-methylphenyl)-5-methylpyridin-4-yl]amino]pyrazolo[4,3-b]pyridin-1-yl]propan-2-ol
Show/Hide
|
C22H22FN5O
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
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CP0479682
|
2-[7-[[2-(2-fluoro-5-methylphenyl)-5-methylpyridin-4-yl]amino]pyrazolo[4,3-b]pyridin-2-yl]-N-methylacetamide
Show/Hide
|
C22H21FN6O
|
1
|
| 1 |
EC50 = 125.89 nM
|
|
|
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CP0540707
|
2-[7-[[2-(2-fluoro-5-methylphenyl)-5-methylpyridin-4-yl]amino]pyrazolo[4,3-b]pyridin-1-yl]-N-methylacetamide
Show/Hide
|
C22H21FN6O
|
1
|
| 1 |
EC50 = 125.89 nM
|
|
|
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CP0551663
|
1-[7-[[2-(2,5-difluorophenyl)-5-methylpyridin-4-yl]amino]pyrazolo[4,3-b]pyridin-2-yl]propan-2-ol
Show/Hide
|
C21H19F2N5O
|
1
|
| 1 |
EC50 = 125.89 nM
|
|
|
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CP0393793
|
(2R)-1-[7-[[2-(2-fluoro-5-methylphenyl)-5-methylpyridin-4-yl]amino]pyrazolo[4,3-b]pyridin-2-yl]propan-2-ol
Show/Hide
|
C22H22FN5O
|
1
|
| 1 |
EC50 = 158.49 nM
|
|
|
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CP0405266
|
2-[7-[[2-(2,5-difluorophenyl)pyridin-4-yl]amino]pyrazolo[4,3-b]pyridin-1-yl]acetamide
Show/Hide
|
C19H14F2N6O
|
1
|
| 1 |
EC50 = 199.53 nM
|
|
|
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CP0513591
|
2-[7-[[2-(2,5-difluorophenyl)pyridin-4-yl]amino]pyrazolo[4,3-b]pyridin-2-yl]acetamide
Show/Hide
|
C19H14F2N6O
|
1
|
| 1 |
EC50 = 251.19 nM
|
|
|
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CP0566557
|
2-[7-[[2-(2-fluoro-5-methylphenyl)-5-methylpyridin-4-yl]amino]pyrazolo[4,3-b]pyridin-2-yl]ethanol
Show/Hide
|
C21H20FN5O
|
1
|
| 1 |
EC50 = 251.19 nM
|
|
|
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CP0393786
|
N-[2-(5-chloro-2-fluorophenyl)pyridin-4-yl]-2-(piperidin-4-ylmethyl)pyrazolo[4,3-b]pyridin-7-amine
Show/Hide
|
C23H22ClFN6
|
1
|
| 1 |
EC50 = 1000 nM
|
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|
