Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[2-(2-fluoro-5-methylphenyl)-5-methylpyridin-4-yl]-1-methylpyrazolo[4,3-b]pyridin-7-amine
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 PubChem ID
CID: 137652412
Canonical SMILES
Cc1ccc(F)c(c1)-c1cc(Nc2ccnc3cnn(C)c23)c(C)cn1
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Compound Formula C20H18FN5
Compound Structure
Protein Name
 Protein Info 
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000187 Calu-6
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 39.81 nM
   TI
   LI
   LO
   TS
CL000907 CellSensor SBE-bla HEK 293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 6.31 nM
   TI
   LI
   LO
   TS