Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7-[[2-(5-chloro-2-fluorophenyl)-5-methylpyridin-4-yl]amino]-N-methylpyrazolo[4,3-b]pyridine-1-carboxamide
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 PubChem ID
CID: 54670226
SID: 131466610
Canonical SMILES
CNC(=O)n1ncc2nccc(Nc3cc(ncc3C)-c3cc(Cl)ccc3F)c12
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Compound Formula C20H16ClFN6O
Compound Structure
Protein Name
 Protein Info 
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000907 CellSensor SBE-bla HEK 293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 31.62 nM
   TI
   LI
   LO
   TS