Brief Information of the Cell Line and Protein
Cell Line ID: CL000049 , C6
Synonyms
C-6
C 6
RGC-6
RGC6
RGc6
Category Cancer cell line
Organism
Rattus norvegicus (Rat)
Cellosaurus ID
CVCL_0194
Protein ID: PT01200 , Delta-type opioid receptor
Gene Name OPRD1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P41143
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000049  Protein ID: PT01200
 
Compound ID Compound Name Compound Formula
CP0253934
2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1-yl)pyrimidine
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C25H25N5
 1
1
EC50 = 14 nM
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CP0254507
2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1-yl)benzo[d]thiazole
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C28H26N4S
 1
1
EC50 = 26 nM
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CP0146308
4-(1-benzyl-1H-imidazol-2-yl)-4-phenyl-1-(thiazol-2-yl)piperidine
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C24H24N4S
 1
1
EC50 = 98 nM
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CP0264747
4-(1-benzyl-1H-imidazol-2-yl)-N-ethyl-4-phenylpiperidine-1-carboxamide
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C24H28N4O
 1
1
EC50 = 117 nM
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CP0264750
4-(1-benzyl-1H-imidazol-2-yl)-N-(2-methoxyphenyl)-4-phenylpiperidine-1-carboxamide
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C29H30N4O2
 1
1
EC50 = 117 nM
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CP0172248
4-(1-benzyl-1H-imidazol-2-yl)-N-(3-methoxyphenyl)-4-phenylpiperidine-1-carboxamide
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C29H30N4O2
 1
1
EC50 = 436 nM
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CP0254970
4-(1-benzyl-1H-imidazol-2-yl)-N-methyl-N,4-diphenylpiperidine-1-carboxamide
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C29H30N4O
 1
1
EC50 = 776 nM
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CP0050359
4-(1-benzyl-1H-imidazol-2-yl)-N,4-diphenylpiperidine-1-sulfonamide
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C27H28N4O2S
 1
1
EC50 = 832 nM
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CP0172246
4-phenyl-4-[1H-imidazol-2-yl]-piperidine
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C28H28N4O
 1
1
EC50 = 1479 nM
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CP0391806
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2R)-2-hydroxy-4-methylpentan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
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C29H41NO4
 1
1
Ki = 0.34 nM
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CP0385766
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2R)-2-hydroxy-5-methylhexan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
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C30H43NO4
 1
1
Ki = 0.42 nM
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CP0464562
(1R,5R,13R,17S)-17-{[(2E)-3-(4-chlorophenyl)prop-2-en-1-yl]amino}-4-(cyclopropylmethyl)-10-hydroxy-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-one
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C29H31ClN2O3
 1
1
Ki = 0.63 nM
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CP0719181
6-desoxymorphine
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C17H19NO2
 1
1
Ki = 11.8 nM
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CP0826762
heterocodeine
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C18H21NO3
 1
1
Ki = 65.8 nM
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CP0000305
(-)-(etorphine)
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C17H19NO3
 1
1
Ki = 104.57 nM
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CP0700026
7,8-dihydro-3,6-didesoxymorphine
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C17H21NO
 1
1
Ki = 241 nM
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CP0136050
2-{8-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-4-oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-3-yl}-N-methyl-acetamide
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C30H42N4O4
 1
1
Ki = 320 nM
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CP0051440
1-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-3-methylsulfanylmethyl-1,3-dihydro-benzimidazol-2-one
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C28H39N3O3S
 1
1
Ki = 608 nM
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CP0338887
1-methanesulfonylmethyl-3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one
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C28H39N3O5S
 1
1
Ki = 1175 nM
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CP0394328
1-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-3-(1H-1,2,4-triazol-5-ylmethyl)benzimidazol-2-one
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C29H38N6O3
 1
1
Ki = 1288.25 nM
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CP0296905
1-methanesulfinylmethyl-3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one
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C28H39N3O4S
 1
1
Ki = 1471 nM
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CP0335783
1-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-3-(2-methylsulfanyl-ethyl)-1,3-dihydro-benzimidazol-2-one
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C29H41N3O3S
 1
1
Ki = 1631 nM
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CP0296906
2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-2-oxo-2,3-dihydro-benzimidazol-1-yl)-acetamide
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C28H38N4O4
 1
1
Ki = 2020 nM
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CP0309392
(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-2-oxo-2,3-dihydro-benzimidazol-1-yl)-acetic acid methyl ester
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C29H39N3O5
 1
1
Ki = 3084 nM
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CP0332957
3-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-2-oxo-2,3-dihydro-benzimidazol-1-yl)-propionic acid methyl ester
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C30H41N3O5
 1
1
Ki = 3084 nM
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CP0865226
codeine-6-methyl ether
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C19H23NO3
 1
1
Ki = 4410 nM
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CP0689409
6-desoxycodeine
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C18H21NO2
 1
1
Ki = 4520 nM
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CP0707983
7,8-dihydro-3-desoxymorphine
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C17H21NO2
 1
1
Ki = 5250 nM
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CP0364199
2-(3-(1-((1s,4s)-4-isopropylcyclohexyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide
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C24H36N4O2
 1
1
Ki = 7000 nM
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CP0858864
7,8-dihydro-3-desoxyheterocodeine
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C18H23NO2
 1
1
Ki = 8830 nM
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CP0079310
(-)-Codeine
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C18H21NO3
 1
1
Ki = 52207 nM
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