Compound ID |
Compound Name |
Compound Formula |
CP0253934
|
2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1-yl)pyrimidine
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|
C25H25N5
|
1
|
1 |
EC50 = 14 nM
|
|
|
CP0254507
|
2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1-yl)benzo[d]thiazole
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|
C28H26N4S
|
1
|
1 |
EC50 = 26 nM
|
|
|
CP0146308
|
4-(1-benzyl-1H-imidazol-2-yl)-4-phenyl-1-(thiazol-2-yl)piperidine
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|
C24H24N4S
|
1
|
1 |
EC50 = 98 nM
|
|
|
CP0264747
|
4-(1-benzyl-1H-imidazol-2-yl)-N-ethyl-4-phenylpiperidine-1-carboxamide
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|
C24H28N4O
|
1
|
1 |
EC50 = 117 nM
|
|
|
CP0264750
|
4-(1-benzyl-1H-imidazol-2-yl)-N-(2-methoxyphenyl)-4-phenylpiperidine-1-carboxamide
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|
C29H30N4O2
|
1
|
1 |
EC50 = 117 nM
|
|
|
CP0172248
|
4-(1-benzyl-1H-imidazol-2-yl)-N-(3-methoxyphenyl)-4-phenylpiperidine-1-carboxamide
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|
C29H30N4O2
|
1
|
1 |
EC50 = 436 nM
|
|
|
CP0254970
|
4-(1-benzyl-1H-imidazol-2-yl)-N-methyl-N,4-diphenylpiperidine-1-carboxamide
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|
C29H30N4O
|
1
|
1 |
EC50 = 776 nM
|
|
|
CP0050359
|
4-(1-benzyl-1H-imidazol-2-yl)-N,4-diphenylpiperidine-1-sulfonamide
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|
C27H28N4O2S
|
1
|
1 |
EC50 = 832 nM
|
|
|
CP0172246
|
4-phenyl-4-[1H-imidazol-2-yl]-piperidine
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|
C28H28N4O
|
1
|
1 |
EC50 = 1479 nM
|
|
|
CP0391806
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2R)-2-hydroxy-4-methylpentan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
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|
C29H41NO4
|
1
|
1 |
Ki = 0.34 nM
|
|
|
CP0385766
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2R)-2-hydroxy-5-methylhexan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
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|
C30H43NO4
|
1
|
1 |
Ki = 0.42 nM
|
|
|
CP0464562
|
(1R,5R,13R,17S)-17-{[(2E)-3-(4-chlorophenyl)prop-2-en-1-yl]amino}-4-(cyclopropylmethyl)-10-hydroxy-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-one
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|
C29H31ClN2O3
|
1
|
1 |
Ki = 0.63 nM
|
|
|
CP0719181
|
6-desoxymorphine
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|
C17H19NO2
|
1
|
1 |
Ki = 11.8 nM
|
|
|
CP0826762
|
heterocodeine
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|
C18H21NO3
|
1
|
1 |
Ki = 65.8 nM
|
|
|
CP0000305
|
(-)-(etorphine)
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|
C17H19NO3
|
1
|
1 |
Ki = 104.57 nM
|
|
|
CP0700026
|
7,8-dihydro-3,6-didesoxymorphine
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|
C17H21NO
|
1
|
1 |
Ki = 241 nM
|
|
|
CP0136050
|
2-{8-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-4-oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-3-yl}-N-methyl-acetamide
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|
C30H42N4O4
|
1
|
1 |
Ki = 320 nM
|
|
|
CP0051440
|
1-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-3-methylsulfanylmethyl-1,3-dihydro-benzimidazol-2-one
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|
C28H39N3O3S
|
1
|
1 |
Ki = 608 nM
|
|
|
CP0338887
|
1-methanesulfonylmethyl-3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one
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|
C28H39N3O5S
|
1
|
1 |
Ki = 1175 nM
|
|
|
CP0394328
|
1-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-3-(1H-1,2,4-triazol-5-ylmethyl)benzimidazol-2-one
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|
C29H38N6O3
|
1
|
1 |
Ki = 1288.25 nM
|
|
|
CP0296905
|
1-methanesulfinylmethyl-3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one
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|
C28H39N3O4S
|
1
|
1 |
Ki = 1471 nM
|
|
|
CP0335783
|
1-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-3-(2-methylsulfanyl-ethyl)-1,3-dihydro-benzimidazol-2-one
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|
C29H41N3O3S
|
1
|
1 |
Ki = 1631 nM
|
|
|
CP0296906
|
2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-2-oxo-2,3-dihydro-benzimidazol-1-yl)-acetamide
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|
C28H38N4O4
|
1
|
1 |
Ki = 2020 nM
|
|
|
CP0309392
|
(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-2-oxo-2,3-dihydro-benzimidazol-1-yl)-acetic acid methyl ester
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|
C29H39N3O5
|
1
|
1 |
Ki = 3084 nM
|
|
|
CP0332957
|
3-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-2-oxo-2,3-dihydro-benzimidazol-1-yl)-propionic acid methyl ester
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|
C30H41N3O5
|
1
|
1 |
Ki = 3084 nM
|
|
|
CP0865226
|
codeine-6-methyl ether
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|
C19H23NO3
|
1
|
1 |
Ki = 4410 nM
|
|
|
CP0689409
|
6-desoxycodeine
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|
C18H21NO2
|
1
|
1 |
Ki = 4520 nM
|
|
|
CP0707983
|
7,8-dihydro-3-desoxymorphine
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|
C17H21NO2
|
1
|
1 |
Ki = 5250 nM
|
|
|
CP0364199
|
2-(3-(1-((1s,4s)-4-isopropylcyclohexyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide
Show/Hide
|
C24H36N4O2
|
1
|
1 |
Ki = 7000 nM
|
|
|
CP0858864
|
7,8-dihydro-3-desoxyheterocodeine
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|
C18H23NO2
|
1
|
1 |
Ki = 8830 nM
|
|
|
CP0079310
|
(-)-Codeine
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|
C18H21NO3
|
1
|
1 |
Ki = 52207 nM
|
|
|