Brief Information of the Compound and Protein
Compound Name
(-)-(etorphine)
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PubChem ID
CID: 5288826
SID: 14897787
Canonical SMILES
CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O
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Compound Formula C17H19NO3
Compound Structure
Protein Name
Delta-type opioid receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41143
Gene Name
OPRD1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000049 C6 Rattus norvegicus (Rat)  1
1
Ki = 104.57 nM
   TI
   LI
   LO
   TS
CL000011 CHO Cricetulus griseus (Chinese hamster)  7
1
EC50 = 316 nM
   TI
   LI
   LO
   TS
2
EC50 > 593 nM
   TI
   LI
   LO
   TS
3
ED50 = 316 nM
   TI
   LI
   LO
   TS
4
Ki = 104.1 nM
   TI
   LI
   LO
   TS
5
Ki = 140 nM
   TI
   LI
   LO
   TS
6
Ki = 150 nM
   TI
   LI
   LO
   TS
7
Ki = 605 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 780 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 51 nM
2 Ki = 113.3 nM
3 Ki = 132 nM
4 Ki = 140 nM
5 Ki = 150 nM
6 Ki = 280 nM
7 Ki = 299 nM
8 Ki = 456 nM