Brief Information of the Cell Line and Protein
Cell Line ID: CL000041 , LTK-
Category Transformed cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_3392
Protein ID: PT01161 , D(4) dopamine receptor
Gene Name DRD4
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P21917
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000041  Protein ID: PT01161
 
Compound ID Compound Name Compound Formula
CP0500636
(6aS,13bS)-11-chloro-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepine-4,12-diol
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C19H20ClNO2
 1
1
Ki = 3987 nM
   TI
   LI
   LO
   TS
CP0888544
11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepine-4-carbaldehyde oxime
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C20H21ClN2O2
 1
1
Ki = 4370 nM
   TI
   LI
   LO
   TS
CP0421806
(6aS,13bS)-methyl 11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepine-4-carboxylate
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C21H22ClNO3
 1
1
Ki = 4830 nM
   TI
   LI
   LO
   TS
CP0430904
(6aS,13bS)-11-chloro-7-methyl-4-(pyridin-4-yl)-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepin-12-ol
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C24H23ClN2O
 1
1
Ki = 5060 nM
   TI
   LI
   LO
   TS
CP0046343
(6aS,13bR)-11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol
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C19H20ClNO
 1
1
Ki = 5520 nM
   TI
   LI
   LO
   TS
CP0387493
11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepine-4-carbaldehyde O-ethyl oxime
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C22H25ClN2O2
 1
1
Ki = 5886 nM
   TI
   LI
   LO
   TS
CP0421805
(6aS,13bS)-11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepine-4-carbaldehyde
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C20H20ClNO2
 1
1
Ki = 5972 nM
   TI
   LI
   LO
   TS
CP0421810
(6aS,13bS)-11-chloro-4-(hydroxymethyl)-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepin-12-ol
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C20H22ClNO2
 1
1
Ki = 6281 nM
   TI
   LI
   LO
   TS
CP0452277
11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepine-4-carbaldehyde O-methyl oxime
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C21H23ClN2O2
 1
1
Ki = 7506 nM
   TI
   LI
   LO
   TS
CP0430903
11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepine-4-carbaldehyde O-benzyl oxime
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C27H27ClN2O2
 1
1
Ki = 8344 nM
   TI
   LI
   LO
   TS
CP0387491
(6aS,13bS)-11-chloro-4-(4-methoxyphenyl)-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepin-12-ol
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C26H26ClNO2
 1
1
Ki = 10000 nM
   TI
   LI
   LO
   TS
CP0421807
11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepine-4-carbaldehyde O-phenyl oxime
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C26H25ClN2O2
 1
1
Ki = 10000 nM
   TI
   LI
   LO
   TS
CP0421808
3-((6aS,13bS)-11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepin-4-yl)benzonitrile
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C26H23ClN2O
 1
1
Ki = 10000 nM
   TI
   LI
   LO
   TS
CP0421811
(6aS,13bS)-11-chloro-7-methyl-4-(3-nitrophenyl)-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepin-12-ol
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C25H23ClN2O3
 1
1
Ki = 10000 nM
   TI
   LI
   LO
   TS
CP0439154
1-((6aS,13bS)-11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepin-4-yl)pyrrolidin-2-one
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C23H25ClN2O2
 1
1
Ki = 10000 nM
   TI
   LI
   LO
   TS
CP0470887
(6aS,13bS)-11-chloro-7-methyl-4-(thiophen-2-yl)-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepin-12-ol
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C23H22ClNOS
 1
1
Ki = 10000 nM
   TI
   LI
   LO
   TS
CP0491213
(6aS,13bS)-11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepine-4-carbonitrile
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C20H19ClN2O
 1
1
Ki = 10000 nM
   TI
   LI
   LO
   TS
CP0507675
(6aS,13bS)-4-bromo-11-chloro-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepin-12-ol
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C19H19BrClNO
 1
1
Ki = 10000 nM
   TI
   LI
   LO
   TS