| Compound ID |
Compound Name |
Compound Formula |
|
CP0089614
|
(1R)-9-[(3R,4R)-1,3-dimethylpiperidin-4-yl]-8-(2-fluoro-4-methylphenyl)-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
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|
C25H29FN4O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0272055
|
(1R)-9-[(3R,4R)-1,3-dimethylpiperidin-4-yl]-8-(2-fluoro-4-methoxyphenyl)-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C25H29FN4O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0573427
|
(1R)-8-(2,6-difluorophenyl)-9-[(3R,4R)-1,3-dimethylpiperidin-4-yl]-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
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|
C24H26F2N4O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0313905
|
(1R)-9-[(3R,4R)-1,3-dimethylpiperidin-4-yl]-8-(2-fluorophenyl)-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C24H27FN4O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0456594
|
(1R)-8-(2-fluorophenyl)-1-methyl-9-(1,3,3-trimethylpiperidin-4-yl)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C25H29FN4O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0573233
|
(1R)-9-[(1R)-1-(1,3-dimethylazetidin-3-yl)ethyl]-8-(2-fluorophenyl)-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C24H27FN4O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0414686
|
(1R)-8-(2-fluorophenyl)-1-methyl-9-[(3R,4R)-3-methylpiperidin-4-yl]-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
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|
C23H25FN4O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0414689
|
(1R)-9-[(1,3-dimethylazetidin-3-yl)-methylamino]-1-methyl-8-phenyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C23H27N5O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0449354
|
(1R)-9-[(1,3-dimethylazetidin-3-yl)-methylamino]-8-(2-fluorophenyl)-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C23H26FN5O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0456562
|
(1R)-8-(2,3-dihydro-1,4-benzodioxin-6-yl)-9-[(3R,4R)-1,3-dimethylpiperidin-4-yl]-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C26H30N4O4
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0556228
|
(1R)-9-[(3R,4R)-1-ethyl-3-methylpiperidin-4-yl]-8-(2-fluorophenyl)-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C25H29FN4O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0533100
|
(1R)-9-[(3R,4R)-1,3-dimethylpiperidin-4-yl]-8-(3-methoxyphenyl)-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
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|
C25H30N4O3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0065733
|
2-[[N-[2-[3-ethylsulfonyl-4-(4-methylpiperazin-1-yl)anilino]-5-fluoropyrimidin-4-yl]-5-(hydroxymethyl)-2-methylanilino]methyl]benzonitrile
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|
C33H36FN7O3S
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0533099
|
(1R)-9-[(3R,4R)-1,3-dimethylpiperidin-4-yl]-1-methyl-8-(2-methylphenyl)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C25H30N4O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0379900
|
(1R)-9-[(3R,4R)-1,3-dimethylpiperidin-4-yl]-8-(4-methoxyphenyl)-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C25H30N4O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0414664
|
(1R)-9-[(3R,4R)-1,3-dimethylpiperidin-4-yl]-8-(3-fluorophenyl)-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C24H27FN4O2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0054203
|
(1R)-9-[(3S,4S)-1,3-dimethylpiperidin-4-yl]-8-(2-fluorophenyl)-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C24H27FN4O2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0509158
|
(1R)-9-[(3R,4R)-1,3-dimethylpiperidin-4-yl]-8-(4-fluorophenyl)-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C24H27FN4O2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0415131
|
(1R)-1-methyl-9-[(3-methylazetidin-3-yl)amino]-8-(trifluoromethyl)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C16H18F3N5O2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0445094
|
(1R)-9-[(3R,4R)-1,3-dimethylpiperidin-4-yl]-1-methyl-8-(4-methylphenyl)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C25H30N4O2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0414687
|
(1R)-8-(2-fluorophenyl)-1-methyl-9-[(3R)-1-methylpyrrolidin-3-yl]-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C22H23FN4O2
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0445172
|
(1R)-8-(2-fluorophenyl)-1-methyl-9-(1-methylpyrrolidin-3-yl)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C22H23FN4O2
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0415129
|
(1R)-8-(2-fluorophenyl)-1-methyl-9-(1-methylpiperidin-4-yl)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C23H25FN4O2
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0379253
|
(1R)-9-(azetidin-3-ylamino)-1-methyl-8-(trifluoromethyl)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C15H16F3N5O2
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0414992
|
(1R)-9-(azetidin-3-ylamino)-1-methyl-8-phenyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C20H21N5O2
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0571376
|
9-[(1,3-dimethylazetidin-3-yl)amino]-1-methyl-8-phenyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C22H25N5O2
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0411801
|
(1R)-9-(azetidin-3-ylamino)-1,8-dimethyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C15H19N5O2
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0556229
|
(1R)-9-[(1,3-dimethylazetidin-3-yl)amino]-1-methyl-8-(trifluoromethyl)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C17H20F3N5O2
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0545869
|
9-(azetidin-3-ylmethyl)-1-methyl-8-(trifluoromethyl)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C16H17F3N4O2
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0456595
|
(1R)-1-methyl-9-[methyl-(3-methylazetidin-3-yl)amino]-8-(trifluoromethyl)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C17H20F3N5O2
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0536608
|
9-(azetidin-3-ylamino)-1-methyl-8-(trifluoromethyl)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C15H16F3N5O2
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0410898
|
9-(azetidin-3-ylamino)-8-fluoro-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C14H16FN5O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0548319
|
9-(azetidin-3-ylamino)-1,8-dimethyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C15H19N5O2
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0379271
|
9-(azetidin-3-ylamino)-1-methyl-8-propan-2-yl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C17H23N5O2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0415465
|
9-(azetidin-3-yloxy)-1-methyl-8-(trifluoromethyl)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C15H15F3N4O3
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0566785
|
(1R)-8-(2-fluorophenyl)-1-methyl-9-[(4R)-1,3,3-trimethylpiperidin-4-yl]-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C25H29FN4O2
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0414991
|
9-(azetidin-3-ylamino)-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C14H17N5O2
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0509159
|
(1R)-8-(3,4-dimethoxyphenyl)-9-[(3R,4R)-1,3-dimethylpiperidin-4-yl]-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C26H32N4O4
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0381408
|
(1S)-9-(azetidin-3-ylamino)-1-methyl-8-(trifluoromethyl)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C15H16F3N5O2
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0536778
|
(1S)-9-(azetidin-3-ylamino)-1,8-dimethyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C15H19N5O2
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0414690
|
(1R)-9-[(1,3-dimethylazetidin-3-yl)-methylamino]-1-methyl-8-(trifluoromethyl)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C18H22F3N5O2
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0548321
|
(1S)-9-(azetidin-3-ylamino)-1-methyl-8-phenyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C20H21N5O2
|
1
|
| 1 |
IC50 = 760 nM
|
|
|
|
CP0545878
|
9-(azetidin-3-ylamino)-1-ethyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C15H19N5O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0550777
|
9-(azetidin-3-ylamino)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C13H15N5O2
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0551442
|
9-(pyrrolidin-3-ylamino)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C14H17N5O2
|
1
|
| 1 |
IC50 = 3300 nM
|
|
|
|
CP0548320
|
9-(azetidin-3-ylamino)-1-cyclopropyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
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|
C16H19N5O2
|
1
|
| 1 |
IC50 = 3500 nM
|
|
|
|
CP0550781
|
N-(2-oxo-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-9-yl)piperidine-4-carboxamide
Show/Hide
|
C16H19N5O3
|
1
|
| 1 |
IC50 = 3500 nM
|
|
|
|
CP0415467
|
1-methyl-N-(2-oxo-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-9-yl)piperidine-4-carboxamide
Show/Hide
|
C17H21N5O3
|
1
|
| 1 |
IC50 = 4500 nM
|
|
|
|
CP0572778
|
9-(azepan-4-ylamino)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C16H21N5O2
|
1
|
| 1 |
IC50 = 8900 nM
|
|
|
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CP0551441
|
9-(piperidin-3-ylamino)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C15H19N5O2
|
1
|
| 1 |
IC50 = 14000 nM
|
|
|
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CP0572779
|
8-[(dimethylamino)methyl]-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C13H16N4O2
|
1
|
| 1 |
IC50 = 16000 nM
|
|
|
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CP0555195
|
9-(azetidin-3-ylmethylamino)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C14H17N5O2
|
1
|
| 1 |
IC50 = 17000 nM
|
|
|
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CP0515921
|
9-(2-aminopropylamino)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C13H17N5O2
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
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CP0546311
|
N-(2-oxo-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-9-yl)azetidine-3-carboxamide
Show/Hide
|
C14H15N5O3
|
1
|
| 1 |
IC50 = 19000 nM
|
|
|
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CP0551440
|
9-(pyrrolidin-3-ylmethylamino)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C15H19N5O2
|
1
|
| 1 |
IC50 = 20000 nM
|
|
|
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CP0415468
|
9-(piperidin-4-ylamino)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C15H19N5O2
|
1
|
| 1 |
IC50 = 21000 nM
|
|
|
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CP0555194
|
9-(piperidin-4-ylmethylamino)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C16H21N5O2
|
1
|
| 1 |
IC50 = 31000 nM
|
|
|
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CP0555196
|
9-(cyclobutylamino)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C14H16N4O2
|
1
|
| 1 |
IC50 = 38000 nM
|
|
|
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CP0546312
|
2-(dimethylamino)-N-(2-oxo-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-9-yl)acetamide
Show/Hide
|
C14H17N5O3
|
1
|
| 1 |
IC50 = 46000 nM
|
|
|
|
CP0572777
|
N-(2-oxo-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-9-yl)pyrrolidine-3-carboxamide
Show/Hide
|
C15H17N5O3
|
1
|
| 1 |
IC50 = 46000 nM
|
|
|
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CP0415466
|
9-(azetidin-3-ylamino)-1-phenyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C19H19N5O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
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CP0415469
|
9-(oxetan-3-ylamino)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C13H14N4O3
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
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CP0550780
|
N-(2-oxo-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-9-yl)-2-piperidin-4-ylacetamide
Show/Hide
|
C17H21N5O3
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
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CP0361044
|
3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
Show/Hide
|
C10H9N3O2
|
1
|
| 1 |
IC50 = 453000 nM
|
|
|
