| Compound ID |
Compound Name |
Compound Formula |
|
CP0475635
|
1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[2-methyl-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea
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|
C20H24N6O3
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0475636
|
1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[2-methyl-4-(6-morpholin-4-ylpyrimidin-4-yl)oxyphenyl]urea
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|
C23H28N6O4
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0519657
|
1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[3-fluoro-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea
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|
C19H21FN6O3
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0535898
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-methyl-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea
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|
C20H17ClF3N5O2
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0573983
|
1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[3-fluoro-4-(6-morpholin-4-ylpyrimidin-4-yl)oxyphenyl]urea
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|
C22H25FN6O4
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0007714
|
4-amino-N-[3-methyl-1-[(6-methylpyridin-2-yl)methyl]indazol-4-yl]thieno[3,2-d]pyrimidine-7-carboxamide
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|
C22H19N7OS
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0481327
|
1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[3-fluoro-4-(6-piperidin-1-ylpyrimidin-4-yl)oxyphenyl]urea
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|
C23H27FN6O3
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0535899
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[3-fluoro-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea
Show/Hide
|
C19H14ClF4N5O2
|
1
|
| 1 |
IC50 = 99 nM
|
|
|
|
CP0364442
|
1-[3-fluoro-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]-3-[3-(trifluoromethyl)phenyl]urea
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|
C19H15F4N5O2
|
1
|
| 1 |
IC50 = 169 nM
|
|
|
|
CP0472365
|
1-(4-bromophenyl)-3-[3-fluoro-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea
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|
C18H15BrFN5O2
|
1
|
| 1 |
IC50 = 272 nM
|
|
|
|
CP0573984
|
1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[3-methyl-4-(6-piperidin-1-ylpyrimidin-4-yl)oxyphenyl]urea
Show/Hide
|
C24H30N6O3
|
1
|
| 1 |
IC50 = 327 nM
|
|
|
|
CP0535897
|
1-(3-bromophenyl)-3-[2-methyl-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea
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|
C19H18BrN5O2
|
1
|
| 1 |
IC50 = 374 nM
|
|
|
|
CP0536066
|
1-(4-chlorophenyl)-3-[2-methyl-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea
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|
C19H18ClN5O2
|
1
|
| 1 |
IC50 = 670 nM
|
|
|
|
CP0519658
|
1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[3-methyl-4-(6-morpholin-4-ylpyrimidin-4-yl)oxyphenyl]urea
Show/Hide
|
C23H28N6O4
|
1
|
| 1 |
IC50 = 690 nM
|
|
|
|
CP0517916
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-methyl-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]thiourea
Show/Hide
|
C20H17ClF3N5OS
|
1
|
| 1 |
IC50 = 770 nM
|
|
|
|
CP0517917
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[3-fluoro-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]thiourea
Show/Hide
|
C19H14ClF4N5OS
|
1
|
| 1 |
IC50 = 860 nM
|
|
|
|
CP0517918
|
1-(4-methoxyphenyl)-3-[2-methyl-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea
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|
C20H21N5O3
|
1
|
| 1 |
IC50 = 1280 nM
|
|
|
|
CP0573839
|
1-[2-methyl-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]-3-[4-(trifluoromethyl)phenyl]urea
Show/Hide
|
C20H18F3N5O2
|
1
|
| 1 |
IC50 = 1510 nM
|
|
|
|
CP0517919
|
1-[3-fluoro-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]-3-(4-methoxyphenyl)urea
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|
C19H18FN5O3
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0481323
|
1-[2-methyl-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]-3-[3-(trifluoromethyl)phenyl]thiourea
Show/Hide
|
C20H18F3N5OS
|
1
|
| 1 |
IC50 = 1840 nM
|
|
|
|
CP0564728
|
1-[3-fluoro-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]-3-[3-(trifluoromethyl)phenyl]thiourea
Show/Hide
|
C19H15F4N5OS
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0491058
|
1-[3-fluoro-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]-3-(4-methylphenyl)urea
Show/Hide
|
C19H18FN5O2
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0481325
|
1-(4-bromophenyl)-3-[2-methyl-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]thiourea
Show/Hide
|
C19H18BrN5OS
|
1
|
| 1 |
IC50 = 3050 nM
|
|
|
|
CP0550703
|
1-[2-methyl-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]-3-phenylthiourea
Show/Hide
|
C19H19N5OS
|
1
|
| 1 |
IC50 = 4900 nM
|
|
|
|
CP0428888
|
1-[3-fluoro-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]-3-phenylthiourea
Show/Hide
|
C18H16FN5OS
|
1
|
| 1 |
IC50 = 6200 nM
|
|
|
|
CP0564707
|
1-[3-methyl-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]-3-phenylthiourea
Show/Hide
|
C19H19N5OS
|
1
|
| 1 |
IC50 = 7500 nM
|
|
|
|
CP0459930
|
1-(2,4-dichlorophenyl)-3-[3-fluoro-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea
Show/Hide
|
C18H14Cl2FN5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0535900
|
1-[2-methyl-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]-3-(1,3-thiazol-2-yl)urea
Show/Hide
|
C16H16N6O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0536067
|
1-(1,3-benzothiazol-2-yl)-3-[2-methyl-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea
Show/Hide
|
C20H18N6O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0560390
|
1-cyclopropyl-3-[2-methyl-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea
Show/Hide
|
C16H19N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0564729
|
1-(2,4-dichlorophenyl)-3-[2-methyl-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea
Show/Hide
|
C19H17Cl2N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
