Brief Information of the Compound and Protein
Compound Name
1-(4-bromophenyl)-3-[2-methyl-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]thiourea
    Show/Hide
PubChem ID
CID: 137649411
Canonical SMILES
CNc1cc(Oc2ccc(NC(=S)Nc3ccc(Br)cc3)c(C)c2)ncn1
    Show/Hide
Compound Formula C19H18BrN5OS
Compound Structure
Protein Name
RAF proto-oncogene serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P04049
Gene Name
RAF1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 3050 nM
   TI
   LI
   LO
   TS