Brief Information of the Cell Line and Protein
Cell Line ID: CL000457 , BT-20
 Cell Line Info 
Synonyms
BT 20
BT20
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0178
Protein ID: PT01045 , Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
 Protein Info 
Gene Name PIK3CA
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P42336
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000457
 Cell Line Info 
 Protein ID: PT01045
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0054465
 Compound Info 
4-amino-2,6-dimethyl-N-(1H-pyrazol-4-yl)quinazoline-8-carboxamide
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C14H14N6O
  1
1
IC50 = 24 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0195835
 Compound Info 
4-amino-2,6-dimethyl-N-(1H-pyrazol-5-yl)quinazoline-8-carboxamide
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C14H14N6O
  1
1
IC50 = 35 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0195833
 Compound Info 
4-amino-2,6-dimethyl-N-(1H-pyrrolo[2,3-b]pyridin-5-yl)quinazoline-8-carboxamide
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C18H16N6O
  1
1
IC50 = 43 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0282725
 Compound Info 
4-amino-2,6-dimethyl-N-(6-methylpyridin-3-yl)quinazoline-8-carboxamide
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C17H17N5O
  1
1
IC50 = 88 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0054466
 Compound Info 
4-amino-2-methyl-N-(6-methylpyridin-3-yl)quinazoline-8-carboxamide
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C16H15N5O
  1
1
IC50 = 112 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS