Brief Information of the Cell Line and Protein
Cell Line ID: CL000417 , LN-229
Synonyms
LN 229
LN229
LNT-229
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0393
Protein ID: PT01037 , Prolyl endopeptidase
Gene Name PREP
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P48147
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000417  Protein ID: PT01037
 
Compound ID Compound Name Compound Formula
CP0044004
benzyl N-[(2S)-1-[(2S)-2-cyanopyrrolidin-1-yl]-1-oxopropan-2-yl]carbamate
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C16H19N3O3
 1
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
CP0075193
benzyl N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]carbamate
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C15H17N3O3
 1
1
IC50 = 325 nM
   TI
   LI
   LO
   TS
CP0043934
(2R,5S,7R)-1-Aza-7-benzyloxycarbonylamino-8-oxo-4-thiabicyclo[3.3.0]octane-2-carbonitrile
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C15H15N3O3S
 1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
CP0166361
benzyl N-[2-[(2R)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]carbamate
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C15H17N3O3
 1
1
IC50 = 3400 nM
   TI
   LI
   LO
   TS
CP0181871
benzyl N-[(2R)-1-[(2S)-2-cyanopyrrolidin-1-yl]-1-oxopropan-2-yl]carbamate
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C16H19N3O3
 1
1
IC50 = 7500 nM
   TI
   LI
   LO
   TS