Brief Information of the Cell Line and Protein
Cell Line ID: CL001056 , MEF-1 [Mouse fibroblast]
 Cell Line Info 
Synonyms
MEF1
Mouse Embryo Fibroblast-1
Category Transformed cell line
Organism
Mus musculus (Mouse)
Protein ID: PT01028 , Ephrin type-B receptor 4
 Protein Info 
Gene Name EPHB4
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P54760
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL001056
 Cell Line Info 
 Protein ID: PT01028
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0128740
 Compound Info 
6-butyl-4-methyl-7-(2-methylphenyl)purino[7,8-a]imidazole-1,3-dione
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C19H21N5O2
  1
1
IC50 = 50 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0128742
 Compound Info 
6-butyl-7-(4-fluoro-2-methylphenyl)-4-methylpurino[7,8-a]imidazole-1,3-dione
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C19H20FN5O2
  1
1
IC50 = 68 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0039399
 Compound Info 
8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydroxyphenyl-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione
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C22H19N5O4
  1
1
IC50 = 130 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0078397
 Compound Info 
6-butyl-7-[5-(1H-indazol-4-yl)-2-methylphenyl]-4-methylpurino[7,8-a]imidazole-1,3-dione
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C26H25N7O2
  1
1
IC50 = 150 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0449284
 Compound Info 
4-methyl-7-(2-methylphenyl)-6-pentylpurino[7,8-a]imidazole-1,3-dione
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C20H23N5O2
  1
1
IC50 = 230 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0440945
 Compound Info 
6-butyl-7-(2-chlorophenyl)-4-methylpurino[7,8-a]imidazole-1,3-dione
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C18H18ClN5O2
  1
1
IC50 = 270 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0392382
 Compound Info 
7-(2-chlorophenyl)-6-(2-methoxyphenyl)-4-methylpurino[7,8-a]imidazole-1,3-dione
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C21H16ClN5O3
  1
1
IC50 = 2200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS