| Compound ID |
Compound Name |
Compound Formula |
|
CP0404926
|
(2R)-2-[[2-amino-5-[(2,3-difluorophenyl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]propan-1-ol
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|
C15H15F2N5OS2
|
2
|
| 1 |
IC50 = 13 nM
|
|
|
| 2 |
IC50 = 79 nM
|
|
|
|
CP0570165
|
(2R)-2-[[6-[(2,3-difluorophenyl)methylsulfanyl]-[1,2]oxazolo[5,4-d]pyrimidin-4-yl]amino]propan-1-ol
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|
C15H14F2N4O2S
|
2
|
| 1 |
IC50 = 13 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0568321
|
(2R)-2-[[5-[(2,3-difluorophenyl)methylsulfanyl]-2H-triazolo[4,5-d]pyrimidin-7-yl]amino]propan-1-ol
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|
C14H14F2N6OS
|
2
|
| 1 |
IC50 = 44 nM
|
|
|
| 2 |
IC50 = 660 nM
|
|
|
|
CP0576589
|
(2R)-2-[[2-[(2,3-difluorophenyl)methylsulfanyl]pyrido[3,4-d]pyrimidin-4-yl]amino]propan-1-ol
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|
C17H16F2N4OS
|
2
|
| 1 |
IC50 = 110 nM
|
|
|
| 2 |
IC50 = 430 nM
|
|
|
|
CP0579816
|
(2R)-2-[[5-[(2,3-difluorophenyl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]propan-1-ol
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|
C15H14F2N4OS2
|
2
|
| 1 |
IC50 = 130 nM
|
|
|
| 2 |
IC50 = 270 nM
|
|
|
|
CP0545351
|
(2R)-2-[[2-[(2,3-difluorophenyl)methylsulfanyl]-7H-purin-6-yl]amino]propan-1-ol
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|
C15H15F2N5OS
|
2
|
| 1 |
IC50 = 250 nM
|
|
|
| 2 |
IC50 = 2490 nM
|
|
|
|
CP0579817
|
(2R)-2-[[2-[(2,3-difluorophenyl)methylsulfanyl]-5H-pyrrolo[3,2-d]pyrimidin-4-yl]amino]propan-1-ol
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|
C16H16F2N4OS
|
2
|
| 1 |
IC50 = 1060 nM
|
|
|
| 2 |
IC50 = 15720 nM
|
|
|
|
CP0570163
|
(2R)-2-[[2-[(2,3-difluorophenyl)methylsulfanyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]propan-1-ol
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|
C16H16F2N4OS
|
2
|
| 1 |
IC50 = 2710 nM
|
|
|
| 2 |
IC50 = 7730 nM
|
|
|
|
CP0576587
|
(2R)-2-[[2-[(2,3-difluorophenyl)methylsulfanyl]thieno[2,3-d]pyrimidin-4-yl]amino]propan-1-ol
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|
C16H15F2N3OS2
|
2
|
| 1 |
IC50 = 4260 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0570164
|
(2R)-2-[[2-[(2,3-difluorophenyl)methylsulfanyl]thieno[3,2-d]pyrimidin-4-yl]amino]propan-1-ol
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|
C16H15F2N3OS2
|
2
|
| 1 |
IC50 = 17170 nM
|
|
|
| 2 |
IC50 = 24670 nM
|
|
|
|
CP0551971
|
(2R)-2-[[2-[(2,3-difluorophenyl)methylsulfanyl]-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl]amino]propan-1-ol
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|
C17H20F2N4OS
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0568148
|
(2R)-2-[[2-[(2,3-difluorophenyl)methylsulfanyl]pyrido[2,3-d]pyrimidin-4-yl]amino]propan-1-ol
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|
C17H16F2N4OS
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0568323
|
(2R)-2-[[2-[(2,3-difluorophenyl)methylsulfanyl]-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]amino]propan-1-ol
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|
C17H20F2N4OS
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0569738
|
(2R)-2-[[2-[(2,3-difluorophenyl)methylsulfanyl]pyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]propan-1-ol
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|
C16H16F2N4OS
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0576588
|
(2R)-2-[[2-[(2,3-difluorophenyl)methylsulfanyl]pyrido[3,2-d]pyrimidin-4-yl]amino]propan-1-ol
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|
C17H16F2N4OS
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0576590
|
(2R)-2-[[2-[(2,3-difluorophenyl)methylsulfanyl]quinazolin-4-yl]amino]propan-1-ol
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|
C18H17F2N3OS
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
