Brief Information of the Compound and Protein
Compound Name
(2R)-2-[[2-[(2,3-difluorophenyl)methylsulfanyl]pyrido[3,4-d]pyrimidin-4-yl]amino]propan-1-ol
    Show/Hide
PubChem ID
CID: 163322283
Canonical SMILES
C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2cnccc12
    Show/Hide
Compound Formula C17H16F2N4OS
Compound Structure
Protein Name
C-X-C chemokine receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CXC chemokine receptor
Uniprot ID
P25025
Gene Name
CXCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000102 U-87MG ATCC Homo sapiens (Human)  2
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
2
IC50 = 430 nM
   TI
   LI
   LO
   TS