| Compound ID |
Compound Name |
Compound Formula |
|
CP0192746
|
2-[1-[[5-(2-ethylbenzimidazol-1-yl)-7-morpholin-4-yl-[1,3]thiazolo[4,5-d]pyrimidin-2-yl]methyl]piperidin-4-yl]propan-2-ol
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|
C27H35N7O2S
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0238995
|
2-[1-[[2-[2-(1-methoxyethyl)benzimidazol-1-yl]-9-methyl-6-morpholin-4-ylpurin-8-yl]methyl]piperidin-4-yl]propan-2-ol
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|
C29H40N8O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0339254
|
2-[1-[[2-(2-ethylbenzimidazol-1-yl)-6-morpholin-4-yl-7H-purin-8-yl]methyl]piperidin-4-yl]propan-2-ol
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|
C27H36N8O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0110718
|
2-[1-[[2-(2-ethylbenzimidazol-1-yl)-9-methyl-6-morpholin-4-ylpurin-8-yl]methyl]piperidin-4-yl]propan-2-ol
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|
C28H38N8O2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0339253
|
2-[1-[[2-[2-(dimethylamino)benzimidazol-1-yl]-9-methyl-6-morpholin-4-ylpurin-8-yl]methyl]piperidin-4-yl]propan-2-ol
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|
C28H39N9O2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0193312
|
2-[1-[[2-[2-(1-hydroxyethyl)benzimidazol-1-yl]-9-methyl-6-morpholin-4-ylpurin-8-yl]methyl]piperidin-4-yl]propan-2-ol
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|
C28H38N8O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0086188
|
2-[1-[[2-(2-cyclopropylbenzimidazol-1-yl)-9-methyl-6-morpholin-4-ylpurin-8-yl]methyl]piperidin-4-yl]propan-2-ol
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|
C29H38N8O2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0148454
|
2-[1-[[9-methyl-6-morpholin-4-yl-2-(2-propan-2-ylbenzimidazol-1-yl)purin-8-yl]methyl]piperidin-4-yl]propan-2-ol
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|
C29H40N8O2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0513993
|
1-[[2-(5-fluoro-1H-indol-4-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl]-N,N-dimethylpiperidin-4-amine
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|
C26H31FN6OS
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0238997
|
2-[1-[[5-(2-ethylbenzimidazol-1-yl)-7-morpholin-4-yl-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]methyl]piperidin-4-yl]propan-2-ol
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|
C27H35N7O2S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0239063
|
4-[2-(2-ethylbenzimidazol-1-yl)-6-[(4-methylsulfonylpiperazin-1-yl)methyl]thieno[3,2-d]pyrimidin-4-yl]morpholine
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|
C25H31N7O3S2
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0239062
|
4-[6-[[2,2-dimethyl-4-(oxetan-3-yl)piperazin-1-yl]methyl]-2-(2-ethylbenzimidazol-1-yl)thieno[3,2-d]pyrimidin-4-yl]morpholine
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|
C29H37N7O2S
|
1
|
| 1 |
IC50 = 102 nM
|
|
|
|
CP0169311
|
2-[1-[[2-(2-ethylbenzimidazol-1-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl]piperidin-4-yl]propan-2-ol
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|
C28H36N6O2S
|
1
|
| 1 |
IC50 = 116 nM
|
|
|
|
CP0193269
|
1-[(2-imidazo[1,2-a]pyridin-5-yl-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl)methyl]-N,N-dimethylpiperidin-4-amine
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|
C25H31N7OS
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0339241
|
N,N-dimethyl-1-[[2-(2-methylbenzimidazol-1-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl]piperidin-4-amine
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|
C26H33N7OS
|
1
|
| 1 |
IC50 = 374 nM
|
|
|
|
CP0169312
|
1-[(2-indol-1-yl-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl)methyl]-N,N-dimethylpiperidin-4-amine
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|
C26H32N6OS
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0239064
|
1-[[2-(benzimidazol-1-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl]-N,N-dimethylpiperidin-4-amine
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|
C25H31N7OS
|
1
|
| 1 |
IC50 = 970 nM
|
|
|
|
CP0513992
|
N,N-dimethyl-1-[[2-(3-methylphenyl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl]piperidin-4-amine
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|
C25H33N5OS
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0247119
|
N,N-dimethyl-1-[[2-(3-methylisoquinolin-4-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl]piperidin-4-amine
Show/Hide
|
C28H34N6OS
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
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CP0186992
|
1-[(2-indazol-1-yl-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl)methyl]-N,N-dimethylpiperidin-4-amine
Show/Hide
|
C25H31N7OS
|
1
|
| 1 |
IC50 = 3200 nM
|
|
|
|
CP0239066
|
4-[6-[[4-(dimethylamino)piperidin-1-yl]methyl]-4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl]-1,3-dihydroindol-2-one
Show/Hide
|
C26H32N6O2S
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0315883
|
N,N-dimethyl-1-[[2-(2-methyl-1-benzothiophen-3-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl]piperidin-4-amine
Show/Hide
|
C27H33N5OS2
|
1
|
| 1 |
IC50 = 3800 nM
|
|
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