| Compound ID |
Compound Name |
Compound Formula |
|
CP0242686
|
2-amino-4-[[(1S)-1-(7-fluoro-4-oxo-3-phenylquinolizin-2-yl)ethyl]amino]-6-methylpyrimidine-5-carbonitrile
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|
C23H19FN6O
|
1
|
| 1 |
IC50 = 0.89 nM
|
|
|
|
CP0026318
|
5-chloro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)ethyl]quinazolin-4-one
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|
C21H16ClN7O
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
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CP0142407
|
2,4-diamino-6-[[(1S)-1-[7-fluoro-3-(3-methylphenyl)-4-oxoquinolizin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
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|
C23H20FN7O
|
1
|
| 1 |
IC50 = 1.28 nM
|
|
|
|
CP0136524
|
2,4-diamino-6-[[(1S)-1-(7-fluoro-4-oxo-3-phenylquinolizin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
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|
C22H18FN7O
|
1
|
| 1 |
IC50 = 1.49 nM
|
|
|
|
CP0353655
|
4-amino-6-[[(1S)-1-(6-methyl-4-oxo-3-phenylquinolizin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
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|
C23H20N6O
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0315553
|
4-amino-6-[[(1S)-1-(7-fluoro-6-methyl-4-oxo-3-phenylquinolizin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
Show/Hide
|
C23H19FN6O
|
1
|
| 1 |
IC50 = 2.28 nM
|
|
|
|
CP0252443
|
2,4-diamino-6-[[(1S)-1-[3-(3,5-difluorophenyl)-7-fluoro-4-oxoquinolizin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
Show/Hide
|
C22H16F3N7O
|
1
|
| 1 |
IC50 = 3.36 nM
|
|
|
|
CP0546504
|
2,4-diamino-6-[[(1S)-1-[3-cyclopropyl-7-fluoro-1-(4-fluorophenyl)-4-oxoquinolizin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
Show/Hide
|
C25H21F2N7O
|
1
|
| 1 |
IC50 = 3.39 nM
|
|
|
|
CP0952933
|
(S)-2-(1-((9H-Purin-6-yl)amino)ethyl)-6-methyl-3-phenyl-4H-quinolizin-4-one
Show/Hide
|
C23H20N6O
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0136522
|
2,4-diamino-6-[[(1S)-1-[7-fluoro-3-(3-fluoro-5-methylphenyl)-4-oxoquinolizin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
Show/Hide
|
C23H19F2N7O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0484380
|
2,4-diamino-6-[[(1S)-1-(7-fluoro-1-methyl-4-oxo-3-phenylquinolizin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
Show/Hide
|
C23H20FN7O
|
1
|
| 1 |
IC50 = 5.6 nM
|
|
|
|
CP0256046
|
2,4-diamino-6-[[(1S)-1-(1-cyclopropyl-7-fluoro-4-oxo-3-phenylquinolizin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
Show/Hide
|
C25H22FN7O
|
1
|
| 1 |
IC50 = 5.9 nM
|
|
|
|
CP0142410
|
2-amino-4-[[(1S)-1-(7-fluoro-4-oxo-3-phenylquinolizin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
Show/Hide
|
C22H17FN6O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0252440
|
4-[2-[(1S)-1-[(2,6-diamino-5-cyanopyrimidin-4-yl)amino]ethyl]-7-fluoro-4-oxo-3-phenylquinolizin-1-yl]benzamide
Show/Hide
|
C29H23FN8O2
|
1
|
| 1 |
IC50 = 7.6 nM
|
|
|
|
CP0252406
|
2,4-diamino-6-[[(1S)-1-[1-(3,5-difluorophenyl)-7-fluoro-4-oxoquinolizin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
Show/Hide
|
C22H16F3N7O
|
1
|
| 1 |
IC50 = 9.42 nM
|
|
|
|
CP0176936
|
2,4-diamino-6-[[(1S)-1-[7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenylquinolizin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
Show/Hide
|
C28H21F2N7O
|
1
|
| 1 |
IC50 = 9.5 nM
|
|
|
|
CP0702721
|
(S)-2-(1-((9H-Purin-6-yl)amino)ethyl)-7-fluoro-3-phenyl-4H-quinolizin-4-one
Show/Hide
|
C22H17FN6O
|
1
|
| 1 |
IC50 = 9.8 nM
|
|
|
|
CP0219705
|
2-amino-4-[[(1S)-1-[7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenylquinolizin-2-yl]ethyl]amino]-6-methylpyrimidine-5-carbonitrile
Show/Hide
|
C29H22F2N6O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0549420
|
2,4-diamino-6-[[(1S)-1-(7-fluoro-4-oxo-1,3-diphenylquinolizin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
Show/Hide
|
C28H22FN7O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0252442
|
4-amino-6-[[(1S)-1-[3-cyclopropyl-7-fluoro-1-(4-fluorophenyl)-4-oxoquinolizin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
Show/Hide
|
C25H20F2N6O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0252444
|
4-amino-6-[[(1S)-1-[7-fluoro-1-(3-fluorophenyl)-4-oxoquinolizin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
Show/Hide
|
C22H16F2N6O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0549419
|
2,4-diamino-6-[[(1S)-1-[7-fluoro-1-(4-methoxyphenyl)-4-oxo-3-phenylquinolizin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
Show/Hide
|
C29H24FN7O2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0252441
|
4-amino-6-[[(1S)-1-[1-(3,5-difluorophenyl)-7-fluoro-4-oxoquinolizin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
Show/Hide
|
C22H15F3N6O
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
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CP0484381
|
4-amino-6-[[(1S)-1-(7-fluoro-4-oxo-1-phenylquinolizin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
Show/Hide
|
C22H17FN6O
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0357572
|
2,4-diamino-6-[[(1S)-1-(7-fluoro-4-oxo-1-phenylquinolizin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
Show/Hide
|
C22H18FN7O
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0252405
|
2-amino-4-[[(1S)-1-(7-fluoro-1-methyl-4-oxo-3-phenylquinolizin-2-yl)ethyl]amino]-6-methylpyrimidine-5-carbonitrile
Show/Hide
|
C24H21FN6O
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0425711
|
4-amino-6-[[(1S)-1-[7-fluoro-1-(4-fluorophenyl)-3-methyl-4-oxoquinolizin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
Show/Hide
|
C23H18F2N6O
|
1
|
| 1 |
IC50 = 114 nM
|
|
|
|
CP0006058
|
2-amino-N-[(1S)-1-[8-[2-(1-methylpyrazol-4-yl)ethynyl]-1-oxo-2-phenylisoquinolin-3-yl]ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
Show/Hide
|
C30H24N8O2
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
