| Compound ID |
Compound Name |
Compound Formula |
|
CP0633980
|
2-methyl-2-(3-sulfamoylphenylamino)-N-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-yl)propanamide
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|
C19H17F3N6O3S2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0636258
|
2-chloro-5-(2-methyl-1-oxo-1-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-ylamino)propan-2-ylamino)benzoic acid
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|
C20H15ClF3N5O3S
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0634799
|
2-(3-hydroxyphenylamino)-2-methyl-N-(6H-thiazolo[5,4-e]indazol-2-yl)propanamide
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|
C18H17N5O2S
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0634800
|
2-chloro-5-(2-methyl-1-oxo-1-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-ylamino)propan-2-ylamino)-N-(3-sulfamoylpropyl)benzamide
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|
C23H23ClF3N7O4S2
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0636016
|
2-(3-acetamido-4-chlorophenylamino)-2-methyl-N-(6H-thiazolo[5,4-e]indazol-2-yl)propanamide
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|
C20H19ClN6O2S
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0634075
|
2-chloro-5-(2-methyl-1-oxo-1-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-ylamino)propan-2-ylamino)benzamide
Show/Hide
|
C20H16ClF3N6O2S
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0635195
|
2-(3-hydroxyphenylamino)-N-(6H-thiazolo[5,4-e]indazol-2-yl)propanamide
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|
C17H15N5O2S
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0635232
|
5-(1-(6H-thiazolo[5,4-e]indazol-2-ylcarbamoyl)cyclopropylamino)-2-chloro-N-methylbenzamide
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|
C20H17ClN6O2S
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0634528
|
N-(benzyloxy)-2-chloro-5-(2-methyl-1-oxo-1-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-ylamino)propan-2-ylamino)benzamide
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|
C27H22ClF3N6O3S
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0633743
|
2-hydroxyethyl 2-(3-(2-methyl-1-oxo-1-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-ylamino)propan-2-ylamino)benzamido)acetate
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|
C24H23F3N6O5S
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0634518
|
N-(2-amino-2-oxoethyl)-2-chloro-5-(2-methyl-1-oxo-1-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-ylamino)propan-2-ylamino)benzamide
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|
C22H19ClF3N7O3S
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0634519
|
2-(2-chloro-5-(2-methyl-1-oxo-1-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-ylamino)propan-2-ylamino)benzamido)acetic acid
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|
C22H18ClF3N6O4S
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0634525
|
4-(2-chloro-5-(2-methyl-1-oxo-1-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-ylamino)propan-2-ylamino)benzamido)butanoic acid
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|
C24H22ClF3N6O4S
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0634078
|
2-(3-acetamido-4-chlorophenylamino)-2-phenyl-N-(6H-thiazolo[5,4-e]indazol-2-yl)acetamide
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|
C24H19ClN6O2S
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
|
CP0637629
|
3-(2-chloro-5-(2-methyl-1-oxo-1-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-ylamino)propan-2-ylamino)benzamido)propanoic acid
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|
C23H20ClF3N6O4S
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
|
CP0633744
|
ethyl 5-(1-(6H-thiazolo[5,4-e]indazol-2-ylamino)-2-methyl-1-oxopropan-2-ylamino)-2-chlorobenzoate
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|
C21H20ClN5O3S
|
1
|
| 1 |
IC50 = 107 nM
|
|
|
|
CP0633748
|
2-(4-chloro-3-propionamidophenylamino)-2-methyl-N-(6H-thiazolo[5,4-e]indazol-2-yl)propanamide
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|
C21H21ClN6O2S
|
1
|
| 1 |
IC50 = 113 nM
|
|
|
|
CP0861914
|
2-(3-hydroxyphenylamino)-2-phenyl-N-(6H-thiazolo[5,4-e]indazol-2-yl)acetamide
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|
C22H17N5O2S
|
1
|
| 1 |
IC50 = 115 nM
|
|
|
|
CP0635005
|
N-(3-amino-3-oxopropyl)-3-(2-methyl-1-oxo-1-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-ylamino)propan-2-ylamino)benzamide
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|
C23H22F3N7O3S
|
1
|
| 1 |
IC50 = 118 nM
|
|
|
|
CP0634342
|
2-(3-hydroxyphenylamino)-4-methyl-N-(6H-thiazolo[5,4-e]indazol-2-yl)pentanamide
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|
C20H21N5O2S
|
1
|
| 1 |
IC50 = 137 nM
|
|
|
|
CP0633746
|
2-(4-chloro-3-(2,3-dihydroxypropoxy)phenylamino)-2-methyl-N-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-yl)propanamide
Show/Hide
|
C22H21ClF3N5O4S
|
1
|
| 1 |
IC50 = 142 nM
|
|
|
|
CP0633765
|
2-(3-hydroxyphenylamino)-N-(6H-thiazolo[5,4-e]indazol-2-yl)acetamide
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|
C16H13N5O2S
|
1
|
| 1 |
IC50 = 148 nM
|
|
|
|
CP0633978
|
isopropyl 5-(1-(6H-thiazolo[5,4-e]indazol-2-ylamino)-2-methyl-1-oxopropan-2-ylamino)-2-chlorobenzoate
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|
C22H22ClN5O3S
|
1
|
| 1 |
IC50 = 148 nM
|
|
|
|
CP0633664
|
2-chloro-N-ethyl-5-(2-methyl-1-oxo-1-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-ylamino)propan-2-ylamino)benzamide
Show/Hide
|
C22H20ClF3N6O2S
|
1
|
| 1 |
IC50 = 163 nM
|
|
|
|
CP0634530
|
1-(3-acetamido-4-fluorophenylamino)-N-(6H-thiazolo[5,4-e]indazol-2-yl)cyclopropanecarboxamide
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|
C20H17FN6O2S
|
1
|
| 1 |
IC50 = 164 nM
|
|
|
|
CP0634077
|
1-(3-hydroxyphenylamino)-N-(6H-thiazolo[5,4-e]indazol-2-yl)cyclopropanecarboxamide
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|
C18H15N5O2S
|
1
|
| 1 |
IC50 = 168 nM
|
|
|
|
CP0633740
|
2-chloro-N-methyl-5-(2-methyl-1-oxo-1-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-ylamino)propan-2-ylamino)benzamide
Show/Hide
|
C21H18ClF3N6O2S
|
1
|
| 1 |
IC50 = 185 nM
|
|
|
|
CP0634033
|
2-(3-acetamido-4-chlorophenylamino)-2-methyl-N-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-yl)propanamide
Show/Hide
|
C21H18ClF3N6O2S
|
1
|
| 1 |
IC50 = 227 nM
|
|
|
|
CP0636160
|
ethyl 5-(1-(6H-thiazolo[5,4-e]indazol-2-ylcarbamoyl)cyclopropylamino)-2-chlorobenzoate
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|
C21H18ClN5O3S
|
1
|
| 1 |
IC50 = 236 nM
|
|
|
|
CP0633742
|
2-(4-chloro-3-(methylsulfonamido)phenylamino)-2-methyl-N-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-yl)propanamide
Show/Hide
|
C20H18ClF3N6O3S2
|
1
|
| 1 |
IC50 = 247 nM
|
|
|
|
CP0635004
|
4-(3-(2-methyl-1-oxo-1-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-ylamino)propan-2-ylamino)benzamido)butanoic acid
Show/Hide
|
C24H23F3N6O4S
|
1
|
| 1 |
IC50 = 247 nM
|
|
|
|
CP0637465
|
2-(4-chloro-3-hydroxyphenylamino)-N-(6H-thiazolo[5,4-e]indazol-2-yl)acetamide
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|
C16H12ClN5O2S
|
1
|
| 1 |
IC50 = 257 nM
|
|
|
|
CP0633747
|
2-fluoro-5-(2-methyl-1-oxo-1-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-ylamino)propan-2-ylamino)benzamide
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|
C20H16F4N6O2S
|
1
|
| 1 |
IC50 = 263 nM
|
|
|
|
CP0859399
|
ethyl 5-(1-(6H-thiazolo[5,4-e]indazol-2-ylamino)-2-methyl-1-oxopropan-2-ylamino)-2-fluorobenzoate
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|
C21H20FN5O3S
|
1
|
| 1 |
IC50 = 265 nM
|
|
|
|
CP0633769
|
2-(3-acetamido-4-chlorophenylamino)-N-(6H-thiazolo[5,4-e]indazol-2-yl)acetamide
Show/Hide
|
C18H15ClN6O2S
|
1
|
| 1 |
IC50 = 278 nM
|
|
|
|
CP0637979
|
3-(2-methyl-1-oxo-1-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-ylamino)propan-2-ylamino)benzoic acid
Show/Hide
|
C20H16F3N5O3S
|
1
|
| 1 |
IC50 = 294 nM
|
|
|
|
CP0635370
|
1-(4-fluoro-3-propionamidophenylamino)-N-(6H-thiazolo[5,4-e]indazol-2-yl)cyclopropanecarboxamide
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|
C21H19FN6O2S
|
1
|
| 1 |
IC50 = 307 nM
|
|
|
|
CP0634803
|
1-(4-chlorophenylamino)-N-(6H-thiazolo[5,4-e]indazol-2-yl)cyclopropanecarboxamide
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|
C18H14ClN5OS
|
1
|
| 1 |
IC50 = 317 nM
|
|
|
|
CP0943023
|
2-(3-methoxyphenylamino)-2-methyl-N-(6H-thiazolo[5,4-e]indazol-2-yl)propanamide
Show/Hide
|
C19H19N5O2S
|
1
|
| 1 |
IC50 = 332 nM
|
|
|
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CP0633665
|
2-(4-chloro-3-hydroxyphenylamino)-2-methyl-N-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-yl)propanamide
Show/Hide
|
C19H15ClF3N5O2S
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0861915
|
2-(4-chloro-3-methoxyphenylamino)-2-methyl-N-(6H-thiazolo[5,4-e]indazol-2-yl)propanamide
Show/Hide
|
C19H18ClN5O2S
|
1
|
| 1 |
IC50 = 347 nM
|
|
|
|
CP0634688
|
2-(3-hydroxyphenylamino)-N1-(6H-thiazolo[5,4-e]indazol-2-yl)succinamide
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|
C18H16N6O3S
|
1
|
| 1 |
IC50 = 364 nM
|
|
|
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CP0859352
|
2-(3-methoxyphenylamino)-N-(6H-thiazolo[5,4-e]indazol-2-yl)propanamide
Show/Hide
|
C18H17N5O2S
|
1
|
| 1 |
IC50 = 387 nM
|
|
|
|
CP0635787
|
methyl 5-(1-(6H-thiazolo[5,4-e]indazol-2-ylamino)-2-methyl-1-oxopropan-2-ylamino)-2-chlorophenylcarbamate
Show/Hide
|
C20H19ClN6O3S
|
1
|
| 1 |
IC50 = 426 nM
|
|
|
|
CP0633766
|
2-(4-chlorophenylamino)-2-methyl-N-(6H-thiazolo[5,4-e]indazol-2-yl)propanamide
Show/Hide
|
C18H16ClN5OS
|
1
|
| 1 |
IC50 = 428 nM
|
|
|
|
CP0633741
|
2-(3-acetamido-4-fluorophenylamino)-2-methyl-N-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-yl)propanamide
Show/Hide
|
C21H18F4N6O2S
|
1
|
| 1 |
IC50 = 444 nM
|
|
|
|
CP0635003
|
2-chloro-N-cyclopropyl-5-(2-methyl-1-oxo-1-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-ylamino)propan-2-ylamino)benzamide
Show/Hide
|
C23H20ClF3N6O2S
|
1
|
| 1 |
IC50 = 472 nM
|
|
|
|
CP0012721
|
[3-[4-[(4-cyclopropylphenyl)methoxy]-3-methoxyphenyl]azetidin-1-yl]-[4-[[(2S)-2,3-dihydroxypropoxy]methyl]pyridin-2-yl]methanone
Show/Hide
|
C30H34N2O6
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
