Brief Information of the Cell Line and Protein
Cell Line ID: CL000082 , HEL
Synonyms
Hel
GM06141
GM06141B
Human ErythroLeukemia
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0001
Protein ID: PT00897 , Potassium voltage-gated channel subfamily H member 2
Gene Name KCNH2
Organism Homo sapiens, Human
Protein Classification Ion channel
Uniprot ID Q12809
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000082  Protein ID: PT00897
 
Compound ID Compound Name Compound Formula
CP0387547
(S)-4-(2,5-difluorophenyl)-N-methyl-N-(1-methylpiperidin-4-yl)-2-phenyl-2H-pyrrole-1(5H)-carboxamide
   Show/Hide
C24H27F2N3O
 1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CP0452185
(2S)-4-(2,5-difluorophenyl)-N-(1-(2-fluoroethyl)piperidin-4-yl)-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide
   Show/Hide
C26H30F3N3O2
 1
1
IC50 = 13800 nM
   TI
   LI
   LO
   TS
CP0495651
(2S)-4-(2,5-Difluorophenyl)-2-(hydroxymethyl)-N-methyl-N-(1-methylpiperidin-4-yl)-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide
   Show/Hide
C25H29F2N3O2
 1
1
IC50 = 14600 nM
   TI
   LI
   LO
   TS
CP0468453
(2S)-N-(1-cyclopropylpiperidin-4-yl)-4-(2,5-difluorophenyl)-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide
   Show/Hide
C27H31F2N3O2
 1
1
IC50 = 15200 nM
   TI
   LI
   LO
   TS
CP0277177
(S)-2-((R)-3-amino-4,4-difluorobutyl)-4-(2,5-difluorophenyl)-N,N-dimethyl-2-phenyl-2H-pyrrole-1(5H)-carboxamide
   Show/Hide
C23H25F4N3O
 1
1
IC50 = 15900 nM
   TI
   LI
   LO
   TS
CP0440516
(S)-4-(2,5-difluorophenyl)-2-(hydroxymethyl)-N-methyl-2-phenyl-N-(piperidin-4-yl)-2,5dihydro-1H-pyrrole-1-carboxamide
   Show/Hide
C24H27F2N3O2
 1
1
IC50 = 19200 nM
   TI
   LI
   LO
   TS
CP0201232
(2S)-4-(2,5-difluorophenyl)-N-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide
   Show/Hide
C25H28F3N3O2
 1
1
IC50 = 20500 nM
   TI
   LI
   LO
   TS
CP0480241
(S)-4-(2,5-difluorophenyl)-N-((3S,4S)-3-fluoro-1-methylpiperidin-4-yl)-2-(hydroxymethyl)-N-methyl-2-phenyl-2H-pyrrole-1(5H)-carboxamide
   Show/Hide
C25H28F3N3O2
 1
1
IC50 = 36900 nM
   TI
   LI
   LO
   TS