Brief Information of the Cell Line and Protein
Cell Line ID: CL001000 , NMIi005-A
 Cell Line Info 
Synonyms
SZ4
Category Induced pluripotent stem cell
Organism
Homo sapiens (Human)
Protein ID: PT00892 , Tyrosine-protein kinase JAK3
 Protein Info 
Gene Name JAK3
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P52333
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL001000
 Cell Line Info 
 Protein ID: PT00892
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0002393
 Compound Info 
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
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C16H20N6O
  1
1
IC50 = 1210 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0756820
 Compound Info 
(R)-3-(3-(7,8-Dimethoxy-5-oxo-1,5-dihydro-4H-benzo[c]-pyrrolo[2,3-h][1,6]naphthyridin-4-yl)piperidin-1-yl)-3-oxopropanenitrile
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C24H23N5O4
  1
1
IC50 = 1550 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0083241
 Compound Info 
US10399979, Compound 17a
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C22H23N3O3
  1
1
IC50 = 3720 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0230502
 Compound Info 
US10399979, Compound 17c
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C23H25N3O3
  1
1
IC50 = 18340 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0104423
 Compound Info 
US10399979, Compound 17d
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C24H27N3O3
  1
1
IC50 = 28860 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0104421
 Compound Info 
US10399979, Compound 17e
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C22H24N4O3
  1
1
IC50 = 61570 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0238761
 Compound Info 
US10399979, Compound 17b
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C23H25N3O3
  1
1
IC50 = 76900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS