| Compound ID |
Compound Name |
Compound Formula |
|
CP0177211
|
3-isopropyl-N-(4-methyl-3-(3-(4-(methylamino)-1,3,5-triazin-2-yl)pyridin-2-yloxy)phenyl)benzamide
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|
C26H26N6O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0026519
|
(S)-5-(2-(2-Aminopyrimidin-5-yl)ethynyl)-N-(2-(3-(dimethylamino)piperidin-1-yl)-5-(trifluoromethyl)phenyl)-2-fluorobenzamide
Show/Hide
|
C27H26F4N6O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0111780
|
4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)-N-(3-(trifluoromethyl)phenyl)benzamide
Show/Hide
|
C25H20F3N5O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0098898
|
3-isopropyl-N-(4-methyl-3-(3-(2-(methylamino)pyridin-4-yl)pyridin-2-yloxy)phenyl)benzamide
Show/Hide
|
C28H28N4O2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0060023
|
N-[4-methyl-3-[3-[2-(methylamino)pyridin-4-yl]pyridin-2-yl]oxyphenyl]-3-(1,1,2,2-tetrafluoroethoxy)benzamide
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|
C27H22F4N4O3
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0177210
|
N-[4-methyl-3-[3-[4-(methylamino)-1,3,5-triazin-2-yl]pyridin-2-yl]oxyphenyl]-3-(trifluoromethoxy)benzamide
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|
C24H19F3N6O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0154852
|
N-(5-Cyclohexyl-2-methoxyphenyl)-4-methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)benzamide
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|
C31H33N5O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0047964
|
5-(2-(2-Aminopyrimidin-5-yl)ethynyl)-2-fluoro-N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Show/Hide
|
C25H21F4N5O
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0098896
|
N-[4-methyl-3-[3-[4-(methylamino)-1,3,5-triazin-2-yl]pyridin-2-yl]oxyphenyl]-3-pyrrol-1-ylbenzamide
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|
C27H23N7O2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0162636
|
2-(Methylamino)triazine 64
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|
C31H37FN8O2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0047966
|
(S)-5-(2-(2-Aminopyrimidin-5-yl)ethynyl)-2-fluoro-N-(2-(3-(methylamino)piperidin-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Show/Hide
|
C26H24F4N6O
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0112104
|
N-[4-methyl-3-[3-[4-(methylamino)-1,3,5-triazin-2-yl]pyridin-2-yl]oxyphenyl]-3-(1,1,2,2-tetrafluoroethoxy)benzamide
Show/Hide
|
C25H20F4N6O3
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0254940
|
(S)-N-(2-(3-Aminopiperidin-1-yl)-5-(trifluoromethyl)phenyl)-5-(2-(2-aminopyrimidin-5-yl)ethynyl)-2-fluorobenzamide
Show/Hide
|
C25H22F4N6O
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0161871
|
2-(Methylamino)triazine 59
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|
C24H19F3N6O2
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0289769
|
2-(Methylamino)triazine 65
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|
C31H35FN8O2
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0075729
|
3-(2-(2-Aminopyrimidin-5-yl)ethynyl)-4-methyl-N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Show/Hide
|
C26H24F3N5O
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0111772
|
2-(Methylamino)pyrimidine 58
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|
C30H31F4N7O2
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0212502
|
N-(5-Cyclohexyl-2-methoxyphenyl)-4-methyl-3-(3-(4-(methylamino)-1,3,5-triazin-2-yl)pyridin-2-yloxy)benzamide
Show/Hide
|
C30H32N6O3
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0111770
|
2-(Methylamino)triazine 63
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|
C29H30F4N8O2
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0047967
|
5-[(2-aminopyrimidin-5-yl)ethynyl]-2-fluoro-N-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]benzamide
Show/Hide
|
C25H22F4N6O
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0203349
|
3-isopropyl-N-(3-(3-(4-(methylamino)-1,3,5-triazin-2-yl)pyridin-2-yloxy)phenyl)benzamide
Show/Hide
|
C25H24N6O2
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0047962
|
(R)-5-(2-(2-Aminopyrimidin-5-yl)ethynyl)-N-(2-(3-(dimethylamino)piperidin-1-yl)-5-(trifluoromethyl)phenyl)-2-fluorobenzamide
Show/Hide
|
C27H26F4N6O
|
1
|
| 1 |
IC50 = 98 nM
|
|
|
|
CP0526660
|
2-(Methylamino)pyrimidine 53
Show/Hide
|
C29H26F4N6O2
|
1
|
| 1 |
IC50 = 105 nM
|
|
|
|
CP0171457
|
N-(5-Cyclohexyl-2-methoxyphenyl)-4-methyl-3-(3-(2-(methylamino)pyridin-4-yl)pyridin-2-yloxy)benzamide
Show/Hide
|
C32H34N4O3
|
1
|
| 1 |
IC50 = 111 nM
|
|
|
|
CP0111759
|
2-(Methylamino)pyrimidine 54
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|
C29H26ClF3N6O2
|
1
|
| 1 |
IC50 = 121 nM
|
|
|
|
CP0161870
|
2-(Methylamino)triazine 61
Show/Hide
|
C30H33F3N8O2
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0111774
|
2-(Methylamino)pyrimidine 57
Show/Hide
|
C29H26F4N6O2
|
1
|
| 1 |
IC50 = 244 nM
|
|
|
|
CP0047965
|
3-(2-(2-Aminopyrimidin-5-yl)ethynyl)-N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Show/Hide
|
C25H22F3N5O
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0037385
|
4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)-N-(2-morpholino-5-(trifluoromethyl)phenyl)benzamide
Show/Hide
|
C29H27F3N6O3
|
1
|
| 1 |
IC50 = 317 nM
|
|
|
|
CP0111761
|
2-(Methylamino)pyrimidine 52
Show/Hide
|
C29H27F3N6O2
|
1
|
| 1 |
IC50 = 368 nM
|
|
|
|
CP0111776
|
2-(Methylamino)pyrimidine 55
Show/Hide
|
C30H29F3N6O2
|
1
|
| 1 |
IC50 = 462 nM
|
|
|
|
CP0777100
|
4-methyl-3-(3-(4-(methylamino)-1,3,5-triazin-2-yl)pyridin-2-yloxy)-N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Show/Hide
|
C30H30F3N7O2
|
1
|
| 1 |
IC50 = 810 nM
|
|
|
|
CP0285297
|
2-(Methylamino)triazine 62
Show/Hide
|
C28H25F4N7O2
|
1
|
| 1 |
IC50 = 852 nM
|
|
|
|
CP0162640
|
5-(2-(2-Aminopyrimidin-5-yl)ethynyl)-2-methoxy-N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Show/Hide
|
C26H24F3N5O2
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
