Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[(2-aminopyrimidin-5-yl)ethynyl]-2-fluoro-N-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]benzamide
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 PubChem ID
CID: 11627419
SID: 16730435
Canonical SMILES
CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(ccc1F)C#Cc1cnc(N)nc1)C(F)(F)F
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Compound Formula C25H22F4N6O
Compound Structure
Protein Name
 Protein Info 
Angiopoietin-1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tie family
Uniprot ID
Q02763
Gene Name
TEK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000213 EA.hy 926
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 84 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 13 nM