Brief Information of the Compound and Protein
Compound Name
N-(5-Cyclohexyl-2-methoxyphenyl)-4-methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)benzamide
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PubChem ID
CID: 16108991
SID: 24755742
Canonical SMILES
CNc1nccc(n1)-c1cccnc1Oc1cc(ccc1C)C(=O)Nc1cc(ccc1OC)C1CCCCC1
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Compound Formula C31H33N5O3
Compound Structure
Protein Name
Angiopoietin-1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tie family
Uniprot ID
Q02763
Gene Name
TEK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000213 EA.hy 926 Homo sapiens (Human)  1
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4 nM