| Compound ID |
Compound Name |
Compound Formula |
|
CP0394709
|
(9R,10S,11S,13S,14S,16R,17R)-9-Fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid
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|
C21H27FO5
|
3
|
| 1 |
EC50 = 0.2 nM
|
|
|
| 2 |
EC50 = 0.3 nM
|
|
|
| 3 |
IC50 = 1.4 nM
|
|
|
|
CP0485719
|
(4-Fluoro-phenyl)-[(4aR,5S)-1-(4-fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-methanol
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|
C25H24F2N2O
|
4
|
| 1 |
EC50 = 1.7 nM
|
|
|
| 2 |
EC50 = 3 nM
|
|
|
| 3 |
EC50 = 8 nM
|
|
|
| 4 |
IC50 = 9.2 nM
|
|
|
|
CP0420008
|
Benzo[b]thiophen-3-yl-[(4aR,5S)-1-(4-fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-methanol
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|
C27H25FN2OS
|
4
|
| 1 |
EC50 = 1.8 nM
|
|
|
| 2 |
EC50 = 20 nM
|
|
|
| 3 |
EC50 = 22 nM
|
|
|
| 4 |
IC50 = 1.8 nM
|
|
|
|
CP0379246
|
3-{[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-hydroxy-methyl}-phenol
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|
C25H25FN2O2
|
2
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
IC50 = 5.2 nM
|
|
|
|
CP0404727
|
[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-naphthalen-2-ylmethanol
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|
C29H27FN2O
|
4
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
EC50 = 22 nM
|
|
|
| 3 |
EC50 = 74 nM
|
|
|
| 4 |
IC50 = 2.4 nM
|
|
|
|
CP0420101
|
[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-phenylmethanol
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|
C25H25FN2O
|
3
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
EC50 = 4 nM
|
|
|
| 3 |
IC50 = 7.9 nM
|
|
|
|
CP0432873
|
[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-(4-methylphenyl)methanol
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|
C26H27FN2O
|
4
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
EC50 = 4 nM
|
|
|
| 3 |
EC50 = 8 nM
|
|
|
| 4 |
IC50 = 2.5 nM
|
|
|
|
CP0485142
|
(4-Chloro-phenyl)-[(4aR,5S)-1-(4-fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-methanol
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|
C25H24ClFN2O
|
4
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
EC50 = 4 nM
|
|
|
| 3 |
EC50 = 9 nM
|
|
|
| 4 |
IC50 = 7 nM
|
|
|
|
CP0404726
|
1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-3-phenyl-propan-1-ol
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|
C27H29FN2O
|
4
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
EC50 = 7 nM
|
|
|
| 3 |
EC50 = 11 nM
|
|
|
| 4 |
IC50 = 8.6 nM
|
|
|
|
CP0435331
|
1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-pentan-1-ol
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|
C23H29FN2O
|
4
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
EC50 = 5 nM
|
|
|
| 3 |
EC50 = 8 nM
|
|
|
| 4 |
IC50 = 0.7 nM
|
|
|
|
CP0451826
|
[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-(3-methoxyphenyl)methanol
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|
C26H27FN2O2
|
4
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
EC50 = 4 nM
|
|
|
| 3 |
EC50 = 19 nM
|
|
|
| 4 |
IC50 = 2.3 nM
|
|
|
|
CP0430632
|
1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-nonan-1-ol
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|
C27H37FN2O
|
3
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
EC50 = 6 nM
|
|
|
| 3 |
IC50 = 4.9 nM
|
|
|
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CP0485483
|
1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-2-phenyl-ethanol
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|
C26H27FN2O
|
4
|
| 1 |
EC50 = 9 nM
|
|
|
| 2 |
EC50 = 11 nM
|
|
|
| 3 |
EC50 = 17 nM
|
|
|
| 4 |
IC50 = 5.5 nM
|
|
|
|
CP0430043
|
4-{[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-hydroxy-methyl}-phenol
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|
C25H25FN2O2
|
4
|
| 1 |
EC50 = 12 nM
|
|
|
| 2 |
EC50 = 16 nM
|
|
|
| 3 |
EC50 = 20 nM
|
|
|
| 4 |
IC50 = 6.6 nM
|
|
|
|
CP0432570
|
[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-[4-(trifluoromethyl)phenyl]methanol
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|
C26H24F4N2O
|
3
|
| 1 |
EC50 = 24 nM
|
|
|
| 2 |
EC50 = 31 nM
|
|
|
| 3 |
IC50 = 14 nM
|
|
|
|
CP0394700
|
[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-(4-phenoxyphenyl)methanol
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|
C31H29FN2O2
|
1
|
| 1 |
IC50 = 15.5 nM
|
|
|
