Brief Information of the Cell Line and Protein
Cell Line ID: CL000599 , TZM-bl
Synonyms
TZM
JC53-bl
JC53BL-13
JC.53bl-13
JC53-bl clone 13
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_B478
Protein ID: PT00005 , Reverse transcriptase/RNaseH
Gene Name POL
Organism Human immunodeficiency virus 1
Protein Classification Enzyme
Uniprot ID Q72547
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000599  Protein ID: PT00005
 
Compound ID Compound Name Compound Formula
CP0481949
2-cyanoethyl 5-amino-4-(4-cyanoanilino)-2-[4-[(E)-2-cyanoethenyl]-2,6-dimethylphenoxy]benzoate
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C28H23N5O3
 1
1
EC50 = 2.94 nM
   TI
   LI
   LO
   TS
CP0132905
Rilpivirine
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C22H18N6
 1
1
EC50 = 3.55 nM
   TI
   LI
   LO
   TS
CP0457125
2-methoxyethyl 5-amino-4-(4-cyanoanilino)-2-[4-[(E)-2-cyanoethenyl]-2,6-dimethylphenoxy]benzoate
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C28H26N4O4
 1
1
EC50 = 4.56 nM
   TI
   LI
   LO
   TS
CP0457126
5-amino-N-(2-chloroethyl)-4-(4-cyanoanilino)-2-[4-[(E)-2-cyanoethenyl]-2,6-dimethylphenoxy]benzamide
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C27H24ClN5O2
 1
1
EC50 = 8.5 nM
   TI
   LI
   LO
   TS
CP0457127
4-[2-amino-4-(aziridine-1-carbonyl)-5-[4-[(E)-2-cyanoethenyl]-2,6-dimethylphenoxy]anilino]benzonitrile
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C27H23N5O2
 1
1
EC50 = 8.69 nM
   TI
   LI
   LO
   TS
CP0566088
5-amino-4-(4-cyanoanilino)-2-[4-[(E)-2-cyanoethenyl]-2,6-dimethylphenoxy]-N-(3-hydroxypropyl)benzamide
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C28H27N5O3
 1
1
EC50 = 22.8 nM
   TI
   LI
   LO
   TS