Brief Information of the Compound and Protein
Compound Name
 Compound Info 
Rilpivirine
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 PubChem ID
CID: 6451164
SID: 14926256
Canonical SMILES
Cc1cc(\C=C\C#N)cc(C)c1Nc1ccnc(Nc2ccc(cc2)C#N)n1
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Compound Formula C22H18N6
Compound Structure
Protein Name
 Protein Info 
Reverse transcriptase/RNaseH
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q72547
Gene Name
POL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000599 TZM-bl
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 3.55 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 0.4 nM
2 IC50 = 1 nM
3 IC50 = 15 nM
4 IC50 = 21 nM
5 IC50 = 22 nM
6 IC50 = 23 nM
7 IC50 = 24 nM
8 IC50 = 27 nM
9 IC50 = 38 nM
10 IC50 = 41 nM
11 IC50 = 42 nM
12 IC50 = 84 nM
13 IC50 > 10000 nM