General Information of the Compound
Compound ID
CP0943502
Compound Name
(3S,4S)-1-(2,6-dimethylphenyl)-3-ethyl-4-methyl-5-oxo-N-(3-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl)pyrrolidine-3-carboxamide
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Structure
Formula
C27H32F3N3O2
Molecular Weight
487.566
Canonical SMILES
CC[C@@]1(C(=O)Nc2cc(N3CCCC3)cc(C(F)(F)F)c2)CN(c2c(C)cccc2C)C(=O)[C@H]1C
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InChI
InChI=1S/C27H32F3N3O2/c1-5-26(16-33(24(34)19(26)4)23-17(2)9-8-10-18(23)3)25(35)31-21-13-20(27(28,29)30)14-22(15-21)32-11-6-7-12-32/h8-10,13-15,19H,5-7,11-12,16H2,1-4H3,(H,31,35)/t19-,26-/m1/s1
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InChIKey
NJIBNWMXQJHQCZ-NIYFSFCBSA-N
Physicochemical Property
logP
5.94024
Rotatable Bonds
5
Heavy Atom Count
35
Polar Areas
52.65
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 51034010
SID: 117694180
ChEMBL ID
CHEMBL3895002
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03813, Chemerin-like receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 < 30 nM
   TI
   LI
   LO
   TS