General Information of the Compound
Compound ID
CP0938045
Compound Name
methyl N-[(1R)-2-[(2S)-2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-2-oxo-1-phenyl-ethyl]carbamate
    Show/Hide
Structure
Formula
C17H20N4O3
Molecular Weight
328.372
Canonical SMILES
COC(=O)N[C@@H](C(=O)N1CCC[C@H]1c1ncc[nH]1)c1ccccc1
    Show/Hide
InChI
InChI=1S/C17H20N4O3/c1-24-17(23)20-14(12-6-3-2-4-7-12)16(22)21-11-5-8-13(21)15-18-9-10-19-15/h2-4,6-7,9-10,13-14H,5,8,11H2,1H3,(H,18,19)(H,20,23)/t13-,14+/m0/s1
    Show/Hide
InChIKey
DKFDECDMJFWAFT-UONOGXRCSA-N
Physicochemical Property
logP
2.1705
Rotatable Bonds
4
Heavy Atom Count
24
Polar Areas
87.32
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 59347627
ChEMBL ID
CHEMBL4646413
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00149, Nonstructural protein 5A
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000148 Huh-7 Homo sapiens (Human)  1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS