General Information of the Compound
Compound ID
CP0897128
Compound Name
7-(2-(2-(6-bromobenzo[d][1,3]dioxol-5-yl)vinyl)hydrazinyl)-N-hydroxy-7-oxoheptanamide
    Show/Hide
Structure
Formula
C16H20BrN3O5
Molecular Weight
414.256
Canonical SMILES
O=C(CCCCCC(=O)NN/C=C/c1cc2c(cc1Br)OCO2)NO
    Show/Hide
InChI
InChI=1S/C16H20BrN3O5/c17-12-9-14-13(24-10-25-14)8-11(12)6-7-18-19-15(21)4-2-1-3-5-16(22)20-23/h6-9,18,23H,1-5,10H2,(H,19,21)(H,20,22)/b7-6+
    Show/Hide
InChIKey
HXAKCNRDWDSHIL-VOTSOKGWSA-N
Physicochemical Property
logP
2.2252
Rotatable Bonds
9
Heavy Atom Count
25
Polar Areas
108.92
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
6
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 44582775
ChEMBL ID
CHEMBL519035
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00285, Histone deacetylase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000090 Schneider 2 Drosophila melanogaster (Fruit fly)  1
1
IC50 = 20 nM
   TI
   LI
   LO
   TS