General Information of the Compound
Compound ID
CP0867222
Compound Name
N-[(1R)-2-[(2S)-2-[4-[4-[4-(butanoylamino)phenyl]phenyl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-2-oxo-1-phenyl-ethyl]-4-phenyl-butanamide
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Structure
Formula
C41H43N5O3
Molecular Weight
653.827
Canonical SMILES
CCCC(=O)Nc1ccc(-c2ccc(-c3c[nH]c([C@@H]4CCCN4C(=O)[C@H](NC(=O)CCCc4ccccc4)c4ccccc4)n3)cc2)cc1
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InChI
InChI=1S/C41H43N5O3/c1-2-11-37(47)43-34-25-23-31(24-26-34)30-19-21-32(22-20-30)35-28-42-40(44-35)36-17-10-27-46(36)41(49)39(33-15-7-4-8-16-33)45-38(48)18-9-14-29-12-5-3-6-13-29/h3-8,12-13,15-16,19-26,28,36,39H,2,9-11,14,17-18,27H2,1H3,(H,42,44)(H,43,47)(H,45,48)/t36-,39+/m0/s1
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InChIKey
WZRSGRDIQGTISA-YFXFWNCGSA-N
Physicochemical Property
logP
8.0262
Rotatable Bonds
13
Heavy Atom Count
49
Polar Areas
107.19
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
4
Complexity
49

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 156022054
ChEMBL ID
CHEMBL4649892
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00149, Nonstructural protein 5A
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000148 Huh-7 Homo sapiens (Human)  1
1
EC50 = 1300 nM
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