General Information of the Compound
Compound ID
CP0863259
Compound Name
(5R*)-N5-(4-Bromophenyl)-(6R*)-N6-(3-methylamino-3-oxopropyl)-(4S*,7R*)-[4,7-ethenylene-spiro[2.4]heptane]-5,6-dicarboxamide
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Structure
Formula
C21H24BrN3O3
Molecular Weight
446.345
Canonical SMILES
CNC(=O)CCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1
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InChI
InChI=1S/C21H24BrN3O3/c1-23-16(26)8-11-24-19(27)17-14-6-7-15(21(14)9-10-21)18(17)20(28)25-13-4-2-12(22)3-5-13/h2-7,14-15,17-18H,8-11H2,1H3,(H,23,26)(H,24,27)(H,25,28)/t14-,15+,17-,18-/m1/s1
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InChIKey
NOWNMNSNCSYAOV-CYGHRXIMSA-N
Physicochemical Property
logP
2.4683
Rotatable Bonds
6
Heavy Atom Count
28
Polar Areas
87.3
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
3
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 67496189
ChEMBL ID
CHEMBL3730852
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00605, FML2_HUMAN
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 1210 nM
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Protein ID: PT02590, N-formyl peptide receptor 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 3.2 nM
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